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Methotrexate-induced hemothorax in a woman with low-risk metastatic gestational trophoblastic disease

•Patients with invasive mole have a risk of bleeding to fragility and vascularity of the tumor.•Some patients may experience life-threatening bleeding.•Chemotherapy of patients with invasive/metastatic mole may induce bleeding.•In our patient with pulmonary metastatic mole, massive hemorrhage occurr...

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Bibliographic Details
Published in:Gynecologic oncology reports 2019-11, Vol.30, p.100517, Article 100517
Main Authors: Ohki, Yuji, Yamada, Hisako, Taira, Yusuke, Kudaka, Wataru, Aoki, Yoichi
Format: Article
Language:English
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Summary:•Patients with invasive mole have a risk of bleeding to fragility and vascularity of the tumor.•Some patients may experience life-threatening bleeding.•Chemotherapy of patients with invasive/metastatic mole may induce bleeding.•In our patient with pulmonary metastatic mole, massive hemorrhage occurred 2 h after the first dose of MTX.•Our patient was successfully treated with partial resection of the bleeding tumor and additional 2 cycles of MTX.
ISSN:2352-5789
2352-5789
DOI:10.1016/j.gore.2019.100517