Soy Products Ameliorate Obesity-Related Anthropometric Indicators in Overweight or Obese Asian and Non-Menopausal Women: A Meta-Analysis of Randomized Controlled Trials

• Published in: Nutrients 2019-11, Vol.11 (11), p.2790
• Main Authors: Mu, Yuze, Kou, Tingyan, Wei, Boyang, Lu, Xuezhao, Liu, Jingyao, Tian, Huimin, Zhang, Wenwen, Liu, Bingkun, Li, Huihui, Cui, Wenbo, Wang, Qiuzhen
• Format: Article
• Language: English
• Subjects: Adult; Anthropometry; Asian Continental Ancestry Group - statistics & numerical data; Body fat; Body Mass Index; Body measurements; Body weight; Body Weight - drug effects; Cardiovascular disease; Clinical trials; Diabetes; Dietary Supplements; Female; Heart attacks; Humans; isoflavones; Isoflavones - administration & dosage; Menopause; Meta-analysis; Metabolic disorders; Obesity; Obesity - therapy; Overweight; Overweight - therapy; Plant-based beverages; Premenopause; Proteins; Public health; randomized clinical trials; Randomized Controlled Trials as Topic; Soy Foods - analysis; Soy products; soy protein; Soybean Proteins - administration & dosage; Soybeans; statistical models; Surgery; Systematic review; Treatment Outcome; waist circumference; Waist Circumference - drug effects; Weight control; weight loss; Weight Loss - drug effects; women; Womens health
• ISSN: 2072-6643; 2072-6643
• DOI: 10.3390/nu11112790

The effect of soy products on the weight of overweight or obese people is controversial, so we aimed to conduct a systematic review and a meta-analysis of published randomized controlled trials to analyze whether supplementation with soy products can help them to lose weight. The relevant data before January 2019 in PubMed, Embase and Cochrane Library were searched. A random-effect model was adopted to calculate the weighted average difference of net changes of body weight, body mass index (BMI), body fat percentage, fat mass, waist circumference, etc. Results: A total of 22 trials (870 overweight or obese participants) were reflected in the present meta-analysis. Analysis showed that soy products significantly reduced body weight, BMI, body fat percent and waist circumference in overweight or obese Asian populations (-0.37 kg, = 0.010; -0.27 kg/m , = 0.042; -0.36%, = 0.032; -0.35 cm, = 0.049) and more significant effects were observed in non-menopausal women reduced body weight (-0.59 kg, = 0.041), BMI (-0.59, = 0.041) and waist circumference (-0.59 cm, = 0.041) in overweight or obese populations. This meta-analysis showed that soy products have weight loss effects, mainly due to soy protein, isoflavone and soy fiber.