Dichlorodiphenyltrichloroethane (DDT) levels in rat livers collected from a malaria vector control region

Dichlorodiphenyltrichloroethane (DDT) is an organochlorine insecticide that has been used for indoor residual spraying for the control of mosquito-borne diseases including malaria. However, due to its toxicity and environmental persistence, there are concerns about its potential deleterious effects...

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Bibliographic Details
Published in:Journal of Veterinary Medical Science 2019, Vol.81(11), pp.1575-1579
Main Authors: MOTOHIRA, Kodai, IKENAKA, Yoshinori, YOHANNES, Yared Beyene, NAKAYAMA, Shouta M. M., WEPENER, Victor, SMIT, Nico J., Johan H. J. VAN VUREN, SOUSA, Ana Catarina, ENUNEKU, Alex Ajeh, OGBOMIDA, Emmanuel Temiotan, ISHIZUKA, Mayumi
Format: Article
Language:English
Subjects:
Animals
Beta decay
Bioaccumulation
DDT
DDT - chemistry
DDT - pharmacology
dichlorodiphenyltrichloroethane
Electron capture
Electron capture detectors
Environmental Pollutants - chemistry
Female
Gas chromatography
house rat
indoor residual spraying
Insect Vectors
Insecticides
Insecticides - chemistry
Insecticides - pharmacology
Liver - chemistry
Malaria
Malaria - prevention & control
malaria vector control
Male
Metabolites
Mosquito Control - methods
Organic compounds
Organochlorine pesticides
Pesticides
Rats
Sentinel Surveillance
South Africa
Spraying
Toxicity
Toxicology
Vector-borne diseases
Wildlife
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Summary:Dichlorodiphenyltrichloroethane (DDT) is an organochlorine insecticide that has been used for indoor residual spraying for the control of mosquito-borne diseases including malaria. However, due to its toxicity and environmental persistence, there are concerns about its potential deleterious effects in humans and wildlife. Therefore, the current study aimed to monitor and estimate the level of DDTs in human communities. The accumulation of DDT and its metabolites was evaluated in house rat (as sentinel) livers collected in an area where DDT was sprayed. DDTs were measured using a gas chromatography / Electron Capture Detector. The results revealed high concentrations of DDTs in the rat livers and the levels of DDTs were similar to findings reported from the same area in 2014.
ISSN:0916-7250
1347-7439
DOI:10.1292/jvms.19-0168