The relationship between myocardial fibrosis detected by cardiac magnetic resonance and Tp‐e interval, 5‐year sudden cardiac death risk score in hypertrophic cardiomyopathy patients

• Published in: Annals of noninvasive electrocardiology 2019-09, Vol.24 (5), p.e12672-n/a
• Main Authors: Riza Demir, Ali, Celik, Ömer, Sevinç, Samet, Uygur, Begüm, Kahraman, Serkan, Yilmaz, Emre, Cemek, Mete, Onal, Yilmaz, Erturk, Mehmet
• Format: Article
• Language: English
• Subjects: cardiac magnetic resonance; Cardiomyopathy; Cardiomyopathy, Hypertrophic - diagnostic imaging; Cardiomyopathy, Hypertrophic - physiopathology; Contrast Media; Correlation analysis; Death, Sudden, Cardiac; Defibrillators; Echocardiography; Electrocardiography; Female; Fibrosis; Gadolinium; Heart; Humans; hypertrophic cardiomyopathy; late gadolinium enhancement; Magnetic resonance; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Original; Retrospective Studies; Risk; Risk Assessment; Risk Factors; sudden cardiac death; Tp‐e interval; Ventricle; Wall thickness
• ISSN: 1082-720X; 1542-474X
• DOI: 10.1111/anec.12672

Background The aim of this study was to investigate the relationship between QT (QTc) interval, Tp‐e interval, Tp‐e/QTc ratio, 5‐year sudden cardiac death (SCD) risk score, and late gadolinium enhancement (LGE) detected by CMR in hypertrophic cardiomyopathy (HCM) patients. Method A total of 74 consecutive patients who underwent CMR with HCM diagnosis were included in the study. These patients were divided into two groups according to the presence of LGE on CMR. All patients underwent detailed echocardiography and QTc interval, Tp‐e interval, and Tp‐e/QTc ratios and 5‐year SCD risk scores were calculated. These parameters were compared for two groups. Results CMR revealed LGE in 32 (43.2%) of 74 HCM patients. In the group with LGE, significantly higher QTc interval (p = 0.002), Tp‐e interval (p