Heart Rate Variability: Measurement and Clinical Utility

Electrocardiographic RR intervals fluctuate cyclically, modulated by ventilation, baroreflexes, and other genetic and environmental factors that are mediated through the autonomic nervous system. Short term electrocardiographic recordings (5 to 15 minutes), made under controlled conditions, e.g., ly...

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Bibliographic Details
Published in:Annals of noninvasive electrocardiology 2005-01, Vol.10 (1), p.88-101
Main Authors: Kleiger, Robert E., Stein, Phyllis K., Bigger Jr, J. Thomas
Format: Article
Language:English
Subjects:
autonomic nervous system
Autonomic Nervous System - physiology
Cardiovascular Diseases - physiopathology
Electrocardiography
Heart Conduction System - physiopathology
Heart Rate - physiology
Honoring Bruce Delmar
Humans
Time Factors
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Summary:Electrocardiographic RR intervals fluctuate cyclically, modulated by ventilation, baroreflexes, and other genetic and environmental factors that are mediated through the autonomic nervous system. Short term electrocardiographic recordings (5 to 15 minutes), made under controlled conditions, e.g., lying supine or standing or tilted upright can elucidate physiologic, pharmacologic, or pathologic changes in autonomic nervous system function. Long‐term, usually 24‐hour recordings, can be used to assess autonomic nervous responses during normal daily activities in health, disease, and in response to therapeutic interventions, e.g., exercise or drugs. RR interval variability is useful for assessing risk of cardiovascular death or arrhythmic events, especially when combined with other tests, e.g., left ventricular ejection fraction or ventricular arrhythmias.
ISSN:1082-720X
1542-474X
DOI:10.1111/j.1542-474X.2005.10101.x