Feasibility of improving vascular imaging in the presence of metallic stents using spectral photon counting CT and K-edge imaging

Correct visualization of the vascular lumen is impaired in standard computed tomography (CT) because of blooming artifacts, increase of apparent size, induced by metallic stents and vascular calcifications. Recently, due to the introduction of photon-counting detectors in the X-ray imaging field, a...

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Bibliographic Details
Published in:Scientific reports 2019-12, Vol.9 (1), p.19850-9, Article 19850
Main Authors: Sigovan, Monica, Si-Mohamed, Salim, Bar-Ness, Daniel, Mitchell, Julia, Langlois, Jean-Baptiste, Coulon, Philippe, Roessl, Ewald, Blevis, Ira, Rokni, Michal, Rioufol, Gilles, Douek, Philippe, Boussel, Loic
Format: Article
Language:English
Subjects:
692/308/2778
692/699/75/593/2728
Animals
Aorta
Bioengineering
Computed tomography
Coronary Angiography - methods
Coronary Vessels - diagnostic imaging
Feasibility Studies
Humanities and Social Sciences
Humans
Hydroxyapatite
Imaging
Implants
Life Sciences
Male
Metals - chemistry
multidisciplinary
Prototypes
Rabbits
Reproducibility of Results
Science
Science (multidisciplinary)
Spatial discrimination
Stents
Tomography, X-Ray Computed - methods
Visualization
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Summary:Correct visualization of the vascular lumen is impaired in standard computed tomography (CT) because of blooming artifacts, increase of apparent size, induced by metallic stents and vascular calcifications. Recently, due to the introduction of photon-counting detectors in the X-ray imaging field, a new prototype spectral photon-counting CT (SPCCT) based on a modified clinical CT system has been tested in a feasibility study for improving vascular lumen delineation and visualization of coronary stent architecture. Coronary stents of different metal composition were deployed inside plastic tubes containing hydroxyapatite spheres to simulate vascular calcifications and in the abdominal aorta of one New Zealand White (NZW) rabbit. Imaging was performed with an SPCCT prototype, a dual-energy CT system, and a conventional 64-channel CT system (B64). We found the apparent widths of the stents significantly smaller on SPCCT than on the other two systems in vitro (p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-019-56427-6