Common Data Elements for National Institute of Mental Health–Funded Translational Early Psychosis Research

The National Institutes of Health has established the PhenX Toolkit as a web-based resource containing consensus measures freely available to the research community. The National Institute of Mental Health (NIMH) has introduced the Mental Health Research Core Collection as part of the PhenX Toolkit...

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Bibliographic Details
Published in:Biological psychiatry : cognitive neuroscience and neuroimaging 2020-01, Vol.5 (1), p.10-22
Main Authors: Öngür, Dost, Carter, Cameron S., Gur, Raquel E., Perkins, Diana, Sawa, Akira, Seidman, Larry J., Tamminga, Carol, Huggins, Wayne, Hamilton, Carol
Format: Article
Language:English
Subjects:
Biological Psychiatry
Cognition
Common Data Elements
Congresses as Topic
Data element
Early psychosis
Humans
Information Dissemination
National Institute of Mental Health (U.S.)
Neuroimaging
PhenX
Psychotic Disorders
Research Design
Schizophrenia
Translational Medical Research
United States
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Summary:The National Institutes of Health has established the PhenX Toolkit as a web-based resource containing consensus measures freely available to the research community. The National Institute of Mental Health (NIMH) has introduced the Mental Health Research Core Collection as part of the PhenX Toolkit and recently convened the PhenX Early Psychosis Working Group to generate the PhenX Early Psychosis Specialty Collection. The Working Group consisted of two complementary panels for clinical and translational research. We review the process, deliberations, and products of the translational research panel. The Early Psychosis Specialty Collection rationale for measure selection as well as additional information and protocols for obtaining each measure are available on the PhenX website (https://www.phenxtoolkit.org). The NIMH strongly encourages investigators to use instruments from the PhenX Mental Health Research Collections in NIMH-funded studies and discourages use of alternative measures to collect similar data without justification. We also discuss some of the potential advances that can be achieved by collecting common data elements across large-scale longitudinal studies of early psychosis.
ISSN:2451-9022
2451-9030
DOI:10.1016/j.bpsc.2019.06.009