Gastric aggressive fibromatosis: report of a case and review of the literature

To describe a rare case of aggressive fibromatosis of the stomach and discuss the differential diagnoses. A 47-year-old man presented with nonspecific abdominal pain. Gastroscopy revealed stomach wall swelling. An antral gastrectomy was performed. Histological examination revealed spindle-shaped cel...

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Bibliographic Details
Published in:International journal of clinical and experimental pathology 2019, Vol.12 (1), p.372-377
Main Authors: Wang, Yang-Kun, Jiang, Bo, Yang, Yan-Cheng, Wang, Su-Nan, Li, Ying-Ying, Meng, Nian-Long, Yuan, Xu-Tao, Jiang, Run-De, Li, Zu-Guo
Format: Article
Language:English
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Case Report
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Summary:To describe a rare case of aggressive fibromatosis of the stomach and discuss the differential diagnoses. A 47-year-old man presented with nonspecific abdominal pain. Gastroscopy revealed stomach wall swelling. An antral gastrectomy was performed. Histological examination revealed spindle-shaped cells and morphology typical of aggressive fibromatosis. We performed a literature search to identify conditions with features similar to those of aggressive fibromatosis. Aggressive fibromatosis does not metastasize, but it is locally invasive and has a tendency to relapse; however, our patient has not had recurrence > 1 year after surgery. Aggressive fibromatosis of the stomach may be confused with an inflammatory fibroid polyp, a gastrointestinal stromal tumor, schwannoma, leiomyoma, inflammatory myofibroblastic tumor, scirrhous carcinoma of the stomach, follicular dendritic cell sarcoma, inflammatory malignant fibrous histiocytoma, myofibroma/myofibromatosis, and solitary fibrous tumor of the stomach. Aggressive fibromatosis of the stomach is a rare spindle cell tumor that must be differentiated from a variety of conditions.
ISSN:1936-2625