Effects of Nigella Sativa on Type-2 Diabetes Mellitus: A Systematic Review

Diabetes mellitus is one of the most prevalent metabolic disorders that affect people of all genders, ages, and races. Medicinal herbs have gained wide attention from researchers and have been considered to be a beneficial adjuvant agent to oral antidiabetic drugs because of their integrated effects...

Full description

Saved in:
Bibliographic Details
Published in:International journal of environmental research and public health 2019-12, Vol.16 (24), p.4911
Main Authors: Hamdan, Amiza, Haji Idrus, Ruszymah, Mokhtar, Mohd Helmy
Format: Article
Language:English
Subjects:
Antidiabetics
Blood glucose
Blood Glucose - drug effects
Cardiovascular diseases
Clinical trials
Diabetes
Diabetes mellitus
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - drug therapy
Diabetic retinopathy
Drugs
Dyslipidemia
Fasting
Glucose
Glycated Hemoglobin A - drug effects
Health risks
Hemoglobin
Herbal medicine
Humans
Hypertension
Hypoglycemia
Hypoglycemic Agents - administration & dosage
Hypoglycemic Agents - adverse effects
Hypoglycemic Agents - therapeutic use
Insulin
Insulin resistance
Insulin Resistance - physiology
Male
Medicinal herbs
Nigella sativa
Plant Extracts - administration & dosage
Plant Extracts - adverse effects
Plant Extracts - therapeutic use
Plants, Medicinal
Randomization
Researchers
Review
Risk analysis
Risk factors
Studies
Systematic review
Tea
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Diabetes mellitus is one of the most prevalent metabolic disorders that affect people of all genders, ages, and races. Medicinal herbs have gained wide attention from researchers and have been considered to be a beneficial adjuvant agent to oral antidiabetic drugs because of their integrated effects. Concerning the various beneficial effects of , this systematic review aims to provide comprehensive information on the effects of on glucose and insulin profile status in humans. A computerized database search performed through Scopus and Medline via Ebscohost with the following set of keywords: OR black seed oil OR thymoquinone OR black cumin AND diabetes mellitus OR hyperglycemia OR blood glucose OR hemoglobin A1C had returned 875 relevant articles. A total of seven articles were retrieved for further assessment and underwent data extraction to be included in this review. was shown to significantly improve laboratory parameters of hyperglycemia and diabetes control after treatment with a significant fall in fasting blood glucose, blood glucose level 2 h postprandial, glycated hemoglobin, and insulin resistance, and a rise in serum insulin. In conclusion, these findings suggested that could be used as an adjuvant for oral antidiabetic drugs in diabetes control.
ISSN:1660-4601
1661-7827
1660-4601
DOI:10.3390/ijerph16244911