Unusual gastric metastasis in triple-negative (estrogen receptor/progesterone receptor/HER2neu negative) GATA-binding protein 3-positive breast cancer

Triple-negative breast cancer (TNBC) accounts for 20%-25% of breast cancer cases. Around 10%-15% of patients with breast cancer present with upfront metastasis. Lymph node, bone, and liver are common sites of metastasis in hormone-positive breast cancer while brain, lungs, and liver in TNBC. Althoug...

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Bibliographic Details
Published in:Indian journal of nuclear medicine 2020-01, Vol.35 (1), p.82-83
Main Authors: Baa, Annie, Naik, Ramavath, Vanidassane, Ilavarasi, Arora, Saurabh, Shamim, Shamim, Mallick, Saumyaranjan, Batra, Atul
Format: Article
Language:English
Subjects:
Biopsy
Breast cancer
Cancer metastasis
Cancer patients
Carcinoma
Computed tomography
Diagnosis
Diagnostic errors
Estrogens
Histochemistry
Hormones
Immunohistochemistry
Interesting Image
Liver
Lungs
Metastasis
Phenols (Class of compounds)
Positron emission
Protein binding
Proteins
Stomach cancer
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Summary:Triple-negative breast cancer (TNBC) accounts for 20%-25% of breast cancer cases. Around 10%-15% of patients with breast cancer present with upfront metastasis. Lymph node, bone, and liver are common sites of metastasis in hormone-positive breast cancer while brain, lungs, and liver in TNBC. Although visceral metastasis is common in TNBC, metastasis to stomach is unusual. Morphological similarity of primary gastric carcinoma and lobular invasive breast carcinoma often leads to misdiagnosis. Meticulous review of histopathology and immunohistochemistry is essential for diagnosis. We present a case of carcinoma breast with unusual gastric nodular metastasis detected on18F-fluorodeoxyglucose positron emission tomography-computed tomography.
ISSN:0972-3919
0974-0244
DOI:10.4103/ijnm.IJNM_156_19