Elevated Coefficient of Variation in Total Fecal Bile Acids Precedes Diagnosis of Necrotizing Enterocolitis

Accumulation of bile acids (BAs) may mediate development of necrotizing enterocolitis (NEC). Serial fecal samples were collected from premature infants with birth weight (BW) ≤ 1800 g, estimated gestational age (EGA) ≤ 32 weeks, and

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Bibliographic Details
Published in:Scientific reports 2020-01, Vol.10 (1), p.249-249, Article 249
Main Authors: Knapp, Shannon, Kehring, Allysa, Stepp, Jennifer, Calton, Christine M., Gephart, Sheila M., Bandlamuri, Sruti, Boyle, Kate E., Dietz, Grey I., Johnson, Haeley, Romo, Ryan E., Spencer, Mackenzie, Bedrick, Alan D., Halpern, Melissa D.
Format: Article
Language:English
Subjects:
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692/4020/1503/1581/3189
692/53/2423
Acids
Bile
Bile acids
Bile Acids and Salts - chemistry
Bile Acids and Salts - metabolism
Birth weight
Coefficient of variation
Diagnosis
Enteral feeding
Enteral nutrition
Enterocolitis
Enterocolitis, Necrotizing - diagnosis
Enterocolitis, Necrotizing - metabolism
Feces
Feces - chemistry
Female
Gastrointestinal diseases
Gestational age
Humanities and Social Sciences
Humans
Infant
Infants
Male
multidisciplinary
Necrosis
Necrotizing enterocolitis
Science
Science (multidisciplinary)
Statistical analysis
Variation
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Description
Summary:Accumulation of bile acids (BAs) may mediate development of necrotizing enterocolitis (NEC). Serial fecal samples were collected from premature infants with birth weight (BW) ≤ 1800 g, estimated gestational age (EGA) ≤ 32 weeks, and
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-019-57178-0