Antidiabetic activity of standardized dried tubers extract of Aconitum napellus in streptozotocin‐induced diabetic rats

India has got rich cultural inheritage in the forms of Ayurveda texts which are a rich and ample source of herbs, shrubs, trees and affluent in medicinally active phytoconstituents. Aconitum napellus is used for the cure of many ailments including rheumatoid arthritis, sciatica and gout. The present...

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Bibliographic Details
Published in:3 Biotech 2020-02, Vol.10 (2), p.56-56, Article 56
Main Authors: Shoaib, Ambreen, Salem-Bekhit, Mounir M., Siddiqui, Hefazat H., Dixit, Rakesh K., Bayomi, Mohsen, Khalid, Mohammad, Badruddeen, Shakeel, Faiyaz
Format: Article
Language:English
Subjects:
Aconitum napellus
Agriculture
Antidiabetics
Arthritis
Bioinformatics
Biomaterials
Biotechnology
Body weight
Cancer Research
Chemistry
Chemistry and Materials Science
Diabetes
Diabetes mellitus
Glucose
Gout
Organoleptic properties
Original
Original Article
Physical characteristics
Physical properties
Physicochemical properties
Rheumatoid arthritis
Rodents
Sciatica
Shrubs
Standardization
Stem Cells
Streptozocin
Tubers
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Summary:India has got rich cultural inheritage in the forms of Ayurveda texts which are a rich and ample source of herbs, shrubs, trees and affluent in medicinally active phytoconstituents. Aconitum napellus is used for the cure of many ailments including rheumatoid arthritis, sciatica and gout. The present work attempts to evaluate the physicochemical and preliminary phytochemical studies on the tubers of Aconitum napellus along with its antidiabetic activity. The herbal standardization was carried out on the basis of organoleptic properties, physical characteristics and physicochemical properties. The body weight of ACON-I (1.25 mg/kg) and ACON-II (2.5 mg/kg) was recorded as 190.40 and 209.40 g, respectively, compared with 163.00 g in diabetic rats at day 28. The body weight of ACON-I and ACON-II was significantly increased compared with diabetic rats ( p  
ISSN:2190-572X
2190-5738
DOI:10.1007/s13205-019-2043-7