Membranous nephropathy with rapid progression

We report a 49-year-old man with microscopic hematuria, subnephrotic proteinuria, and rapidly progressive renal failure. His biopsy had features of PhosphoLipase A2 Receptor (PLA2R) positive membranous nephropathy with circumferential cellular crescents. Further work-up revealed IgG antiGlomerular B...

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Bibliographic Details
Published in:Indian journal of nephrology 2020-01, Vol.30 (1), p.47-49
Main Authors: Vairakkani, R, Valavan, K, Fernando, M, Raj, T
Format: Article
Language:English
Subjects:
Antibodies
Biopsy
Case Report
Development and progression
Edema
Hematuria
Hemodialysis
Hepatitis
Immunoglobulin G
Immunoglobulins
Kidney diseases
Kidney failure
Morbidity
Patients
Phospholipases
Proteinuria
Urine
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Summary:We report a 49-year-old man with microscopic hematuria, subnephrotic proteinuria, and rapidly progressive renal failure. His biopsy had features of PhosphoLipase A2 Receptor (PLA2R) positive membranous nephropathy with circumferential cellular crescents. Further work-up revealed IgG antiGlomerular Basement Membrane (anti-GBM) antibody titer of 188 U/mL (normal
ISSN:0971-4065
1998-3662
DOI:10.4103/ijn.IJN_85_19