Specific IgE to gelatin as a cause of anaphylaxis to zoster vaccine

[...]she had a negative assay to Fel d 2 (cat serum albumin) and pork, serological indicators of pork-cat syndrome.6 Thus, IgE results for subject number 1 eliminate both the alpha-gal syndrome and the pork-cat syndrome as the cause of her reactions to meat. Note that although alpha-gal allergy is a...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2018-05, Vol.141 (5), p.1956-1957
Main Authors: Retterer, Maya K.C., Workman, Lisa J., Bacon, John R., Platts-Mills, Thomas A.E.
Format: Article
Language:English
Subjects:
Allergies
Anaphylaxis
Arachnids
Gelatin
Herpes Zoster Vaccine
Humans
Immunoglobulin E
Mammals
Meat
Patients
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Summary:[...]she had a negative assay to Fel d 2 (cat serum albumin) and pork, serological indicators of pork-cat syndrome.6 Thus, IgE results for subject number 1 eliminate both the alpha-gal syndrome and the pork-cat syndrome as the cause of her reactions to meat. Note that although alpha-gal allergy is a potential cause of anaphylaxis following zoster vaccination, only a minority of alpha-gal–allergic patients react.7 Our patient presents the enigma of a possibly tick-sensitized gelatin-allergic individual reacting to zoster vaccine while negative to alpha-gal. IgE results Four cases of alpha-gal syndrome Subject 1 Subject 2 Subject 3 Subject 4 Subject 5 Total IgE 645 1180 3021 1201 838 Alpha-gal (z5)∗
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2017.08.047