Metal-enhanced fluorescence solution-based sensing platform

In recent years our laboratories have reported the favorable effects for fluorophores placed in close proximity to surface immobilized silver nanostructures. These include; greater quantum yields, reduced lifetimes (increased photostability) and directional emission. However, while these findings ar...

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Bibliographic Details
Published in:Journal of fluorescence 2004-11, Vol.14 (6), p.677-679
Main Authors: Asian, Kadir, Lakowicz, Joseph R, Szmacinski, Henryk, Geddes, Chris D
Format: Article
Language:English
Subjects:
Colloids
Fluorescence
Fluorescent Dyes
Metals
Nanostructures
Silicon Dioxide
Silver
Solutions
Surface Properties
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Summary:In recent years our laboratories have reported the favorable effects for fluorophores placed in close proximity to surface immobilized silver nanostructures. These include; greater quantum yields, reduced lifetimes (increased photostability) and directional emission. However, while these findings are likely to find multifarious applications for surface assays based on enhanced fluorescence detection, a solution based enhanced sensing platform has yet to be realized. In this short, note, we show how SiO2-coated silver colloids, indeed provide for a solution based enhanced fluorescence sensing platform with a 3-5 fold enhancement typically observed.
ISSN:1053-0509
1573-4994
DOI:10.1023/B:JOFL.0000047217.74943.5c