Quantitative assessment of treatment efficacy in keloids using high-frequency ultrasound and shear wave elastography: a preliminary study

The purpose of this study was to investigate the performance of high-frequency ultrasound (HFUS) and shear wave elastography (SWE) in the quantitative evaluation of therapeutic responses of keloids. 43 patients with 76 keloids were recruited into this study. In keloids and symmetrical sites, the ski...

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Bibliographic Details
Published in:Scientific reports 2020-01, Vol.10 (1), p.1375-1375, Article 1375
Main Authors: Huang, Song-Ya, Xiang, Xi, Guo, Rui-Qian, Cheng, Shan, Wang, Li-Yun, Qiu, Li
Format: Article
Language:English
Subjects:
692/699
692/699/4033
Adult
Aged
Elastic Modulus
Elasticity Imaging Techniques
Female
Humanities and Social Sciences
Humans
Keloid - diagnostic imaging
Keloid - physiopathology
Keloid - therapy
Male
Mechanical properties
Middle Aged
multidisciplinary
Science
Science (multidisciplinary)
Skin
Skin - diagnostic imaging
Skin - physiopathology
Ultrasonic imaging
Ultrasonic Therapy
Ultrasound
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Summary:The purpose of this study was to investigate the performance of high-frequency ultrasound (HFUS) and shear wave elastography (SWE) in the quantitative evaluation of therapeutic responses of keloids. 43 patients with 76 keloids were recruited into this study. In keloids and symmetrical sites, the skin thickness was measured using HFUS and skin stiffness expressed as elastic moduli (Young’s modulus and shear wave velocity) was measured using SWE. The coefficient of variation values were calculated by using difference values of skin elastic moduli and skin thickness. A significant increase of both skin stiffness and thickness appeared in pre-treated keloids compared with post-treated keloids (P 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-58209-x