Utility of serum free light chain ratio in response definition in patients with multiple myeloma

•Patients with an abnormal sFLC ratio because of LC suppression have outcomes similar to those with a normal ratio.•sFLC ratio has prognostic value in patients achieving CR who have an absence of clonal BMPCs assessed by MFC.

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Bibliographic Details
Published in:Blood advances 2020-01, Vol.4 (2), p.322-326
Main Authors: Abdallah, Nadine, Kapoor, Prashant, Murray, David L., Buadi, Francis K., Dingli, David, Dispenzieri, Angela, Gertz, Morie A., Go, Ronald S., Gonsalves, Wilson I., Hayman, Suzanne R., Kourelis, Taxiarchis V., Lacy, Martha Q., Leung, Nelson, Lust, John A., Muchtar, Eli, Warsame, Rahma, Kyle, Robert A., Rajkumar, S. Vincent, Kumar, Shaji K.
Format: Article
Language:English
Subjects:
Humans
Immunoglobulin Light Chains - therapeutic use
Middle Aged
Multiple Myeloma - genetics
Multiple Myeloma - therapy
Stimulus Report
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Description
Summary:•Patients with an abnormal sFLC ratio because of LC suppression have outcomes similar to those with a normal ratio.•sFLC ratio has prognostic value in patients achieving CR who have an absence of clonal BMPCs assessed by MFC.
ISSN:2473-9529
2473-9537
DOI:10.1182/bloodadvances.2019001099