Kounis Syndrome Induced by Protamine Sulfate

Protamine sulfate is considered a "life-saving" antidote for heparinized patients with major bleeds. Although the beneficial attributes and application of protamine sulfate in various clinical settings cannot be argued, it also has an impressive side-effect profile. Kounis syndrome (KS) is...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2020-02, Vol.12 (2), p.e6972
Main Authors: Amro, Mohammad, Mansoor, Kanaan, Amro, Ahmed, Okoro, Kelechukwu, Okhumale, Paul I
Format: Article
Language:English
Subjects:
Allergy/Immunology
Cardiac arrhythmia
Cardiology
Cardiovascular disease
Case reports
Coronary vessels
Hypertension
Immunoglobulins
Internal Medicine
Intubation
Medical imaging
Medicine
Pulmonary arteries
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Summary:Protamine sulfate is considered a "life-saving" antidote for heparinized patients with major bleeds. Although the beneficial attributes and application of protamine sulfate in various clinical settings cannot be argued, it also has an impressive side-effect profile. Kounis syndrome (KS) is an acute coronary syndrome in the setting of an allergic reaction, which can be induced by numerous allergens. Herein, we report a case of KS secondary to the use of protamine sulfate after cryoablation for atrial fibrillation.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.6972