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Nasofacial rhinoentomophthoramycosis: A report of two cases from Central India

Rhinoentomophthoromycosis due to Conidiobolus coronatus is a rare, chronic, granulomatous disease, occurring mainly in tropical countries including India. We report two cases of rhinoentomophthoromycosis in an 18-year-old female and a farmer of 35 years residents of Chhattisgarh shifted from Madhya...

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Published in:Journal of oral and maxillofacial pathology : JOMFP 2020-02, Vol.24 (4), p.124-127
Main Authors: Wankhade, Archana, Patro, Priyadarshini, Arora, Ripu, Nagarkar, Nitin
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description Rhinoentomophthoromycosis due to Conidiobolus coronatus is a rare, chronic, granulomatous disease, occurring mainly in tropical countries including India. We report two cases of rhinoentomophthoromycosis in an 18-year-old female and a farmer of 35 years residents of Chhattisgarh shifted from Madhya Pradesh and Orrisa. It was diagnosed by microscopy and isolation C. coronatus in culture. The patient presented with a swollen nose with obstruction that had progressed slowly over 1 year. His nasal swelling was bilateral, diffuse, mildly tender, erythematous, nonpitting, with mucosal crusting and hypertrophy of inferior turbinates but no regional lymphadenopathy. Culture of tissue from the nasal biopsy on sabouraud dextrose agar yielded multiple colonies of a mold with satellite smaller colonies at periphery. The isolate demonstrated the macroscopic and microscopic morphologic characteristics of C. coronatus. The patients were earlier treated with itraconazole or its combination with potassium iodide and the patients were treated successfully with amphotericin B.
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identifier ISSN: 0973-029X
ispartof Journal of oral and maxillofacial pathology : JOMFP, 2020-02, Vol.24 (4), p.124-127
issn 0973-029X
1998-393X
language eng
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source Publicly Available Content Database; PubMed Central
subjects Amphotericin B
Biopsy
Case Report
Colonies
Conidiobolus coronatus
Dextrose
Diseases
Endoscopy
Farmers
Histopathology
Hypertrophy
Isolation
Itraconazole
Lymphadenopathy
Lymphoma
Microscopy
Mucosa
Nose
Posaconazole
Potassium iodide
Rhinoentomophthoromycosis
Sarcoidosis
Tissue culture
Tuberculosis
title Nasofacial rhinoentomophthoramycosis: A report of two cases from Central India
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