Metabolomics-based study reveals the effect of lead (Pb) in the culture environment on Whitmania pigra

• Published in: Scientific reports 2020-03, Vol.10 (1), p.4794, Article 4794
• Main Authors: Luo, Xuemei, Meng, Jieqin, Chen, Xiufen, Cheng, Liangke, Yan, Shaopeng, Gao, Luying, Xue, Miao, Yang, Yaojun
• Format: Article
• Language: English
• Subjects: 631/45; 704/172; 704/47; Animals; Aquaculture; Herbal medicine; Humanities and Social Sciences; Lead; Lead - metabolism; Lead - toxicity; Leeches - metabolism; Lipid metabolism; Lipids; Medicine, Chinese Traditional; Metabolic pathways; Metabolic response; Metabolism; Metabolites; Metabolomics; Metabolomics - methods; multidisciplinary; Nucleotides; Polluted environments; Residues; Science; Science (multidisciplinary); Traditional Chinese medicine; Water Pollutants, Chemical - metabolism; Water Pollutants, Chemical - toxicity; Whitmania pigra
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-020-61745-1

Whitmania pigra , called Mahuang (MH) in Chinese, has been used as a traditional Chinese medicine for many years and is susceptible to Pb exposure in aquaculture environments. To understand the impact of Pb in the culture environment on MHs, we carried out a 50-day culture of MHs in environments with different levels of Pb pollution. Then, tissue samples of MHs reared in the different Pb-polluted environments were collected and analysed by UPLC-Q/TOF-MS. The results showed that the Pb residue in MHs increased with increasing Pb in the culture environment. There was no significant difference in MH Pb content ( P