T Cell Cytokines Impact Epithelial Cell Responses during Helicobacter pylori Infection

The goal of this is to highlight literature that demonstrates how cytokines made by T lymphocytes impact the gastric epithelium, especially during infection. These cytokines effect many of the diverse functions of the epithelium and the epithelium's interactions with The focal point of this wil...

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Bibliographic Details
Published in:The Journal of immunology (1950) 2020-03, Vol.204 (6), p.1421-1428
Main Author: Algood, Holly M Scott
Format: Article
Language:English
Subjects:
Animals
Antigen-Presenting Cells - immunology
Antigens, Bacterial - immunology
Cytokines - metabolism
Disease Models, Animal
Disease Progression
Epithelial Cells - immunology
Epithelial Cells - microbiology
Epithelial Cells - pathology
Gastric Mucosa - cytology
Gastric Mucosa - immunology
Gastric Mucosa - microbiology
Gastric Mucosa - pathology
Helicobacter Infections - complications
Helicobacter Infections - immunology
Helicobacter Infections - microbiology
Helicobacter Infections - pathology
Helicobacter pylori - immunology
Humans
Stomach Neoplasms - immunology
Stomach Neoplasms - microbiology
Stomach Neoplasms - pathology
T-Lymphocytes - immunology
T-Lymphocytes - metabolism
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Summary:The goal of this is to highlight literature that demonstrates how cytokines made by T lymphocytes impact the gastric epithelium, especially during infection. These cytokines effect many of the diverse functions of the epithelium and the epithelium's interactions with The focal point of this will be on how T cell cytokines impact antimicrobial function and barrier function and how T cell cytokines influence the development and progression of cancer. Furthermore, the modulation of epithelial-derived chemokines by infection will be discussed.
ISSN:0022-1767
1550-6606
DOI:10.4049/jimmunol.1901307