Roadblocks to PrEP: What Medical Records Reveal About Access to HIV Pre-exposure Prophylaxis

• Published in: Journal of general internal medicine : JGIM 2020-03, Vol.35 (3), p.832-838
• Main Authors: Skolnik, Avy A., Bokhour, Barbara G., Gifford, Allen L., Wilson, Brigid M., Van Epps, Puja
• Format: Article
• Language: English
• Subjects: Acquired Immunodeficiency Syndrome - drug therapy; Anti-HIV Agents - therapeutic use; Content analysis; Disease transmission; Electronic health records; Electronic medical records; Exposure; Health risks; HIV; HIV Infections - drug therapy; HIV Infections - epidemiology; HIV Infections - prevention & control; Human immunodeficiency virus; Humans; Internal Medicine; Medical Records; Medicine; Medicine & Public Health; Original Research; Patients; Pre-Exposure Prophylaxis; Prophylaxis; Qualitative analysis; Retrospective Studies
• ISSN: 0884-8734; 1525-1497; 1525-1497
• DOI: 10.1007/s11606-019-05475-9

Background Pre-exposure prophylaxis (PrEP) has been shown to be efficacious in preventing HIV; however, its uptake remains modest. Given that there are fewer cost barriers to receiving PrEP within VHA than via commercial insurance, VHA represents an ideal setting in which to study other barriers that may impact patients seeking PrEP. Objective We sought to understand potential barriers to obtaining PrEP within the Veterans Health Administration (VHA) through examination of documentation in electronic medical records. Design Retrospective structured chart review, including chart abstractions of notes, referrals, and communications; content analysis of charts from a subsample of patients receiving PrEP in VHA. Participants One hundred sixty-one patients prescribed PrEP at 90 sites varying in PrEP prescribing rates. Approach We extracted descriptive information and conducted a qualitative analysis of all PrEP-relevant free-text notes including who initiated the PrEP conversation (patient vs. provider), time interval between request and prescription, reasons for denying PrEP, and patient responses to barriers. Key Results Patients initiated 94% of PrEP conversations and 35% of patients experienced delays receiving PrEP ranging from six weeks to 16 months. Over 70% of cases evidenced barriers to access. Barriers included provider knowledge gaps about PrEP, provider knowledge gaps about VHA systems related to PrEP, confusion or disagreement over clinic purview for PrEP, and provider attitudes or stigma associated with patients seeking PrEP. Conclusions Although PrEP is recommended for HIV prevention in high-risk persons, many PrEP-eligible individuals faced barriers to obtaining a prescription. Current practices place substantial responsibility on patients to request and advocate for this service, in contrast to many other preventive services. Understanding the prevalence and content of PrEP knowledge gaps and attitudinal barriers can inform organizational interventions to increase PrEP access and decrease HIV transmission.