Extramedullary nasal plasmacytoma arising after polyp excision and the role of the inflammation in tumor development: A case report

A correlation between inflammation and cancer has been identified in the case of nasal cancer, however a specific connection between nasal inflammation and extramedullary nasal plasmacytoma (ENP), to the best of our knowledge, has not yet been determined. The present case report describes a patient...

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Bibliographic Details
Published in:Molecular and clinical oncology 2020-05, Vol.12 (5), p.451-455
Main Authors: Di Stadio, Arianna, Gambacorta, Valeria, de Crescenzo, Stefano, Sidoni, Angelo, Cristi, Maria Cristina, Di Giovanni, Alfredo, Maranzano, Massimo, Ricci, Giampietro
Format: Article
Language:English
Subjects:
Cancer therapies
Case reports
Endoscopy
Hospitals
Inflammation
Investigations
Magnetic resonance imaging
Nose
Oncology
Pain
Pathology
Surgery
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Summary:A correlation between inflammation and cancer has been identified in the case of nasal cancer, however a specific connection between nasal inflammation and extramedullary nasal plasmacytoma (ENP), to the best of our knowledge, has not yet been determined. The present case report describes a patient affected by ENP, in who the tumor arose in the same area, from which a nasal polyp was previously surgically removed, five months after the polyp excision. The patient underwent surgical endoscopic tumor asportation without being treated with radio-chemotherapy. ENP was totally removed via surgery and no signs of recurrence were identified by endoscopy or magnetic resonance imaging during the last check-up 1 year after tumor asportation. It was hypothesized that in this elderly patient, who was exposed to viral infections and pollution for several years, ENP may be correlated to the inflammatory process that occurred after surgery, and this likely contributed to a neoplastic mutation in B-cells.
ISSN:2049-9450
2049-9469
DOI:10.3892/mco.2020.2007