Understanding SARS with Wolfram approach

Stepping acquired immunodeficiency syndrome (AIDS), severe acute respiratory syndrome (SARS) as another type of disease has been threatening mankind since late last year. Many scientists worldwide are making great efforts to study the etiology of this disease with different approaches. 13 species of...

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Bibliographic Details
Published in:Acta Biochimica et Biophysica Sinica 2004-01, Vol.36 (1), p.1-10
Main Authors: Li, Da-Wei, Pan, Yu-Xi, Duan, Yun, Hung, Zhen-De, Xu, Ming-Qing, He, Lin
Format: Article
Language:English
Subjects:
Algorithms
Computer Simulation
Databases, Genetic
Gene Expression Profiling - methods
Gene Expression Regulation, Viral - genetics
Humans
Models, Genetic
Research Papers
SARS Virus - classification
SARS Virus - genetics
Sequence Alignment - methods
Sequence Analysis, DNA - methods
Sequence Homology, Nucleic Acid
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Summary:Stepping acquired immunodeficiency syndrome (AIDS), severe acute respiratory syndrome (SARS) as another type of disease has been threatening mankind since late last year. Many scientists worldwide are making great efforts to study the etiology of this disease with different approaches. 13 species of SARS virus have been sequenced. However, most people still largely rely on the traditional methods with some disadvantages. In this work, we used Wolfram approach to study the relationship among SARS viruses and between SARS viruses and other types of viruses, the effect of variations on the whole genome and the advantages in the analysis of SARS based on this novel approach. As a result, the similarities between SARS viruses and other coronaviruses are not really higher than those between SARS viruses and non-coronaviruses.
ISSN:1672-9145
1745-7270
DOI:10.1093/abbs/36.1.1