Bovine coronaviruses from the respiratory tract: Antigenic and genetic diversity

Highlights ► This initial U.S. study examined genetic and antigenic differences among BoCV. ► Two clades were identified, BoCV1 and BoCV2 using viral DNA sequencing. ► Three subclades of BoCV2 were identified: BoCV2a, BoCV2b, and BoCV2c. ► Antigenic differences among BoCV clades were detected by vir...

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Bibliographic Details
Published in:Vaccine 2013-01, Vol.31 (6), p.886-892
Main Authors: Fulton, R.W, Ridpath, J.F, Burge, L.J
Format: Article
Language:English
Subjects:
Allergy and Immunology
Alveoli
Animals
Antigenic
Antigens
Antigens, Viral - immunology
antiserum
Applied microbiology
Biological and medical sciences
Bovine
Bovine coronavirus
Carrier State - veterinary
Carrier State - virology
Cattle
Cattle Diseases - virology
Cluster Analysis
Coronavirus Infections - veterinary
Coronavirus Infections - virology
Coronavirus, Bovine - classification
Coronavirus, Bovine - genetics
Coronavirus, Bovine - immunology
Coronavirus, Bovine - isolation & purification
Diarrhea
Fundamental and applied biological sciences. Psychology
Genetic
Genetic diversity
Genetic Variation
Licenses
Microbiology
Miscellaneous
Molecular Sequence Data
Neutralization
nose
Nutrition research
Phylogeny
Proteins
Respiratory disease
Respiratory diseases
Respiratory System - virology
Respiratory tract
Respiratory Tract Infections - veterinary
Respiratory Tract Infections - virology
RNA, Viral - genetics
Sequence Analysis, DNA
Studies
United States
Vaccination
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Virology
Viruses
washing
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Summary:Highlights ► This initial U.S. study examined genetic and antigenic differences among BoCV. ► Two clades were identified, BoCV1 and BoCV2 using viral DNA sequencing. ► Three subclades of BoCV2 were identified: BoCV2a, BoCV2b, and BoCV2c. ► Antigenic differences among BoCV clades were detected by viral neutralization tests.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2012.12.006