Photochemistry and pharmacology of 9, 19-cyclolanostane glycosides isolated from genus Cimicifuga

The constituents of Cimicifuga plants have been extensively investigated, and the principal metabolites are 9, 19-cyclolanostane triterpenoid glycosides, which often exhibit extensive pharmacological activities. 9, 19-Cyclolanostane triterpenoid glycosides are distributed widely in genus Cimicifuga...

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Published in:Chinese Journal of Natural Medicines 2016-10, Vol.14 (10), p.721-731
Main Authors: SU, Yang, CHI, Wen-Cheng, WU, Lun, WANG, Qiu-Hong, KUANG, Hai-Xue
Format: Article
Language:English
Subjects:
9, 19-Cyclolanostane glycosides
Animals
Biological effects
Chemical structure
Cimicifuga - chemistry
Cimicifuga spp
Drugs, Chinese Herbal - chemistry
Drugs, Chinese Herbal - isolation & purification
Drugs, Chinese Herbal - pharmacology
Glycosides - chemistry
Glycosides - isolation & purification
Glycosides - pharmacology
Humans
Photochemistry
Triterpenes - chemistry
Triterpenes - isolation & purification
Triterpenes - pharmacology
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Summary:The constituents of Cimicifuga plants have been extensively investigated, and the principal metabolites are 9, 19-cyclolanostane triterpenoid glycosides, which often exhibit extensive pharmacological activities. 9, 19-Cyclolanostane triterpenoid glycosides are distributed widely in genus Cimicifuga rather than in other members of the Ranunculaceae family. So far, more than 140 cycloartane triterpene glycosides have been isolated from Cimicifuga spp.. The aim of this review was to summarize all 9, 19-cyclolanostane triterpenoid glycosides based on the available relevant scientific literatures from 2000 to 2014. Biological studies of cycloartane triterpene glycosides from Cimicifuga spp. are also discussed. [Display omitted]
ISSN:1875-5364
2095-6975
1875-5364
DOI:10.1016/S1875-5364(16)30087-5