Accurate surgical navigation with real-time tumor tracking in cancer surgery

In the past decades, image-guided surgery has evolved rapidly. In procedures with a relatively fixed target area, like neurosurgery and orthopedics, this has led to improved patient outcomes. In cancer surgery, intraoperative guidance could be of great benefit to secure radical resection margins sin...

Full description

Saved in:
Bibliographic Details
Published in:NPJ precision oncology 2020-04, Vol.4 (1), p.8-8, Article 8
Main Authors: Kok, Esther N. D., Eppenga, Roeland, Kuhlmann, Koert F. D., Groen, Harald C., van Veen, Ruben, van Dieren, Jolanda M., de Wijkerslooth, Thomas R., van Leerdam, Monique, Lambregts, Doenja M. J., Heerink, Wouter J., Hoetjes, Nikie J., Ivashchenko, Oleksandra, Beets, Geerard L., Aalbers, Arend G. J., Nijkamp, Jasper, Ruers, Theo J. M.
Format: Article
Language:English
Subjects:
692/4028/546
692/699/1503/1504/1885/1777
Accuracy
Cancer Research
Cancer surgery
Chemotherapy
Colorectal cancer
Gene Therapy
Human Genetics
Internal Medicine
Medicine
Medicine & Public Health
Navigation systems
Neurosurgery
Oncology
Precision medicine
Radiation therapy
Sensors
Surgeons
Surgical outcomes
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In the past decades, image-guided surgery has evolved rapidly. In procedures with a relatively fixed target area, like neurosurgery and orthopedics, this has led to improved patient outcomes. In cancer surgery, intraoperative guidance could be of great benefit to secure radical resection margins since residual disease is associated with local recurrence and poor survival. However, most tumor lesions are mobile with a constantly changing position. Here, we present an innovative technique for real-time tumor tracking in cancer surgery. In this study, we evaluated the feasibility of real-time tumor tracking during rectal cancer surgery. The application of real-time tumor tracking using an intraoperative navigation system is feasible and safe with a high median target registration accuracy of 3 mm. This technique allows oncological surgeons to obtain real-time accurate information on tumor location, as well as critical anatomical information. This study demonstrates that real-time tumor tracking is feasible and could potentially decrease positive resection margins and improve patient outcome.
ISSN:2397-768X
2397-768X
DOI:10.1038/s41698-020-0115-0