Hip fractures following denosumab discontinuation: three clinical cases reports

Summary A significant loss of bone mineral density and the appearance of multiple vertebral fractures after discontinuation of denosumab treatment have been described. To date, no hip fractures have been reported. We present three cases of patients who suffered femoral fractures after denosumab supp...

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Bibliographic Details
Published in:Journal of the Royal Society of Medicine 2019-11, Vol.112 (11), p.472-475
Main Authors: Sosa Henríquez, Manuel, Gómez de Tejada Romero, María Jesús, Escudero-Socorro, María, Torregrosa Suau, Oscar
Format: Article
Language:English
Subjects:
Absorptiometry, Photon
Aged
Aged, 80 and over
Bone Density - drug effects
Bone Density Conservation Agents - pharmacology
Denosumab - pharmacology
Female
Grand Round
Hip Fractures - diagnosis
Hip Fractures - etiology
Humans
Middle Aged
Osteoporosis, Postmenopausal - drug therapy
Withholding Treatment
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Description
Summary:Summary A significant loss of bone mineral density and the appearance of multiple vertebral fractures after discontinuation of denosumab treatment have been described. To date, no hip fractures have been reported. We present three cases of patients who suffered femoral fractures after denosumab suppression.
ISSN:0141-0768
1758-1095
DOI:10.1177/0141076819861027