Welding Fumes, a Risk Factor for Lung Diseases

(1) Background: Welding fumes (WFs) are composed of fine and ultrafine particles, which may reach the distal airways and represent a risk factor for respiratory diseases. (2) Methods: In vitro and in vivo studies to understand WFs pathogenesis were selected. Epidemiological studies, original article...

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Bibliographic Details
Published in:International journal of environmental research and public health 2020-04, Vol.17 (7), p.2552
Main Authors: Riccelli, Maria Grazia, Goldoni, Matteo, Poli, Diana, Mozzoni, Paola, Cavallo, Delia, Corradi, Massimo
Format: Article
Language:English
Subjects:
Aerosols
Cardiovascular diseases
Chronic obstructive pulmonary disease
DNA damage
Dosimetry
Epidemiology
Exposure
Fluorides
Fumes
Gases
Genotoxicity
Health risks
In vitro methods and tests
In vivo methods and tests
Information centers
Lung diseases
Metal oxides
Occupational exposure
Occupational health
Occupational safety
Oxidative stress
Particle size
Respiratory diseases
Respiratory system
Review
Risk analysis
Risk factors
Sedimentation & deposition
Stainless steel
Technical information
Ultrafines
Welding
Welding machines
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Summary:(1) Background: Welding fumes (WFs) are composed of fine and ultrafine particles, which may reach the distal airways and represent a risk factor for respiratory diseases. (2) Methods: In vitro and in vivo studies to understand WFs pathogenesis were selected. Epidemiological studies, original articles, review, and meta-analysis to examine solely respiratory disease in welders were included. A systematic literature search, using PubMed, National Institute for Occupational Safety and Health Technical Information Center (NIOSHTIC), and Web of Science databases, was performed. (3) Results: Dose, time of exposure, and composition of WFs affect lung injury. Inflammation, lung defense suppression, oxidative stress, DNA damage, and genotoxic effects were observed after exposure both to mild and stainless steel WFs. (4) Conclusions: The detection of lung diseases associated with specific occupational exposure is crucial as complete avoidance or reduction of the exposure is difficult to achieve. Further studies in the area of particle research may aid the understanding of mechanisms involved in welding-related lung disease and to expand knowledge in welding-related cardiovascular diseases.
ISSN:1660-4601
1661-7827
1660-4601
DOI:10.3390/ijerph17072552