Breast Metastasis From a Non-small Cell Lung Cancer: A Case Report

Although primary breast cancer (BC) is the most frequent cancer in the world, their mammary metastases are rare. In this paper, we report the case of a 51-year-old male patient diagnosed with a mammary lump and an intracranial hypertension syndrome. Mammography showed the presence of an irregular op...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2020-03, Vol.12 (3), p.e7460
Main Authors: Guerrouaz, Mohammed Amine, Samba, Soumiya, BenSghier, Ahmed, Sbai, Sr, Ali, Mezouar, Loubna
Format: Article
Language:English
Subjects:
Breast cancer
Cancer therapies
Case reports
Chemotherapy
Gastric cancer
Lung cancer
Lymphatic system
Mammography
Medical imaging
Medical prognosis
Melanoma
Metastasis
Neuroendocrine tumors
Oncology
Ovarian cancer
Palliative care
Radiation Oncology
Thyroid cancer
Transcription factors
Ultrasonic imaging
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Summary:Although primary breast cancer (BC) is the most frequent cancer in the world, their mammary metastases are rare. In this paper, we report the case of a 51-year-old male patient diagnosed with a mammary lump and an intracranial hypertension syndrome. Mammography showed the presence of an irregular opacity without microcalcifications. After a cytological and immunohistochemical examination, the breast biopsy showed an adenocarcinoma of pulmonary origin. Computed tomography (CT) scans of the cerebrum, cervicothoracic spine, and abdomen showed a right apical pulmonary tumor associated with Barety's lymphadenopathy, as well as the presence of a mass in the right breast and secondary brain lesions. The patient received total brain irradiation which resulted in a marked clinical improvement. Afterward, he was treated with six cycles of palliative chemotherapy based on carboplatin area under the curve (AUC) 6 and paclitaxel, 175 mg/m² every 21 days, with a good response. After two months, the patient presented with a progression and he was treated with second-line chemotherapy. However, after three chemotherapy courses, the disease rapidly progressed and the patient was altered which required his admission to the palliative care department. The patient died 40 days later. This case shows the poor prognostic survival outcomes in this population of patients.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.7460