Thyroid Nodule Size and Prediction of Cancer: A Study at Tertiary Care Hospital in Saudi Arabia

Background Thyroid noduleshave become relatively common in clinical practice,and their prevalence increases with age. The majority of thyroid nodules are benign, with 5-15% being malignant. There are a number of well-established predictors of malignancy in thyroid nodules, but thyroid nodule size ha...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2020-03, Vol.12 (3), p.e7478-e7478
Main Authors: Al-Hakami, Hadi Afandi, Alqahtani, Raneem, Alahmadi, Asim, Almutairi, Dakheelallah, Algarni, Mohammed, Alandejani, Talal
Format: Article
Language:English
Subjects:
Cellular biology
Endocrinology/Diabetes/Metabolism
Family medical history
Gender
Histopathology
Hyperthyroidism
Lymphoma
Oncology
Otolaryngology
Thyroid cancer
Tumors
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Summary:Background Thyroid noduleshave become relatively common in clinical practice,and their prevalence increases with age. The majority of thyroid nodules are benign, with 5-15% being malignant. There are a number of well-established predictors of malignancy in thyroid nodules, but thyroid nodule size has been a cause for concern for many researchers and results of the studies are still controversial about their probability of malignancy. Up to the current knowledge, there is no published study that evaluates if thyroid nodule size is associated with the risk of malignancy in Saudi Arabia, so in this study, we aim to find that. Methods This is a retrospective study of 987 patients who underwent thyroid nodule fine-needle aspiration (FNA) and subsequent thyroidectomy for thyroid nodules measuring ≥ 1 cm. Results Thyroid cancer was more prevalent in males than females, and in patients who were older than or equal to 45 years. Nodular size of 1 - 1.9 cm was more prevalent among cancer patients than in benign cases (p
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.7478