Comparative determination of xenobiotics adsorption

Xenobiotic solutions of different concentrations were analyzed by TLC method before and after passing trough the column with adsorbent M and compared with adsorption on the active charcoal. The efficiency of adsorption on adsorbent M was higher, compared to active charcoal. The best adsorption, in t...

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Bibliographic Details
Published in:Biomolecules & biomedicine 2006-08, Vol.6 (3), p.54-56
Main Authors: Mijanović, Mirjana, Zaciragić, Asija
Format: Article
Language:English
Subjects:
adsorbent M
Adsorption
Animals
Charcoal
Chromatography, Thin Layer
Female
Male
pesticides
Pesticides - pharmacokinetics
Pesticides - toxicity
TLC
toxicity
Xenobiotics - pharmacokinetics
Xenobiotics - toxicity
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Summary:Xenobiotic solutions of different concentrations were analyzed by TLC method before and after passing trough the column with adsorbent M and compared with adsorption on the active charcoal. The efficiency of adsorption on adsorbent M was higher, compared to active charcoal. The best adsorption, in the value 90 - 100%, have shown certain organochlorine and organophosphorus pesticides, that were dissolved in non-aqueous solvents. Efficiency of adsorbent M was also proven in vivo, when solutions of tested xenobiotics before adsorption have caused death of experimental animals, and after the adsorption on adsorbent M, all treated animals have survived and had just mild symptoms of poisoning.
ISSN:1512-8601
2831-0896
1840-4812
2831-090X
DOI:10.17305/bjbms.2006.3145