Recurrence Rate in a Patient Treated with Colon Resection Followed by Chemotherapy in Comparison to a Patient Treated with Colon Resection without Chemotherapy

Given that colon cancer is one of the most prevalent cancers worldwide, it is essential to employ strategies to try to reduce its incidence and recurrence rate. Though colon cancer is a sporadic disease in the vast majority of cases, multiple risk factors are linked to this disease, namely, obesity...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2020-04, Vol.12 (4), p.e7544-e7544
Main Authors: Alshehri, Khalid A, Altuwaylie, Talal M, Fakieha, Abdulaziz, AlGhamdi, Ghassan, Alshahrani, Saad M, Mikwar, Zaher
Format: Article
Language:English
Subjects:
Chemotherapy
Colorectal cancer
Gastroenterology
General Surgery
Health risk assessment
Laparoscopy
Large intestine
Lymphatic system
Males
Medical prognosis
Metastasis
Mortality
Obesity
Oncology
Patients
Polyps
Questionnaires
Risk factors
Surgery
Systematic review
Tumors
Weight control
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Summary:Given that colon cancer is one of the most prevalent cancers worldwide, it is essential to employ strategies to try to reduce its incidence and recurrence rate. Though colon cancer is a sporadic disease in the vast majority of cases, multiple risk factors are linked to this disease, namely, obesity and cigarette smoking. Additionally, not many studies have been done in Saudi Arabia studying the recurrence rate of colon cancer. Therefore, we conducted a retrospective cohort study at King Khalid Hospital, King Abdulaziz Medical City, National Guard Health Affairs (NGHA), Jeddah, Saudi Arabia to investigate the recurrence rate of colon cancer in patients treated with complete colon resection followed by chemotherapy versus patients treated with colon resection alone via electronic and paper medical records. A total of 120 patients were included in this study; 61 were males (50.8%) and 59 were females (49.2%). According to our findings, the recurrence rate in patients who underwent surgical resection with adjuvant chemotherapy was 15.6% (n = 10), while the recurrence rate in patients with surgery alone was 21.4% (n = 12). Cancer recurrence is associated with significant morbidity and mortality. Therefore, further studies should be done to investigate the recurrence rate in patients with risk factors to identify and deal with the causes of recurrence.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.7544