Loading…

The plastid transcription machinery and its coordination with the expression of nuclear genome: Plastid-Encoded Polymerase, Nuclear-Encoded Polymerase and the Genomes Uncoupled 1-mediated retrograde communication

Plastid genes in higher plants are transcribed by at least two different RNA polymerases, the plastid-encoded RNA polymerase (PEP), a bacteria-like core enzyme whose subunits are encoded by plastid genes ( , , and ), and the nuclear-encoded plastid RNA polymerase (NEP), a monomeric bacteriophage-typ...

Full description

Saved in:
Bibliographic Details
Published in:Philosophical transactions of the Royal Society of London. Series B. Biological sciences 2020-06, Vol.375 (1801), p.20190399-20190399
Main Authors: Tadini, Luca, Jeran, Nicolaj, Peracchio, Carlotta, Masiero, Simona, Colombo, Monica, Pesaresi, Paolo
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c539t-46859d48219443b0902da2e2cb0e0c7247893a1a2d4115e94525ea941d1f28c93
cites cdi_FETCH-LOGICAL-c539t-46859d48219443b0902da2e2cb0e0c7247893a1a2d4115e94525ea941d1f28c93
container_end_page 20190399
container_issue 1801
container_start_page 20190399
container_title Philosophical transactions of the Royal Society of London. Series B. Biological sciences
container_volume 375
creator Tadini, Luca
Jeran, Nicolaj
Peracchio, Carlotta
Masiero, Simona
Colombo, Monica
Pesaresi, Paolo
description Plastid genes in higher plants are transcribed by at least two different RNA polymerases, the plastid-encoded RNA polymerase (PEP), a bacteria-like core enzyme whose subunits are encoded by plastid genes ( , , and ), and the nuclear-encoded plastid RNA polymerase (NEP), a monomeric bacteriophage-type RNA polymerase. Both PEP and NEP enzymes are active in non-green plastids and in chloroplasts at all developmental stages. Their transcriptional activity is affected by endogenous and exogenous factors and requires a strict coordination within the plastid and with the nuclear gene expression machinery. This review focuses on the different molecular mechanisms underlying chloroplast transcription regulation and its coordination with the photosynthesis-associated nuclear genes ( ) expression. Particular attention is given to the link between NEP and PEP activity and the GUN1- (Genomes Uncoupled 1) mediated chloroplast-to-nucleus retrograde communication with respect to the adaptive response, i.e. the increased accumulation of NEP-dependent transcripts upon depletion of PEP activity, and the editing-level changes observed in NEP-dependent transcripts, including and , in cotyledons after norflurazon or lincomycin treatment. The role of cytosolic preproteins and HSP90 chaperone as components of the GUN1-retrograde signalling pathway, when chloroplast biogenesis is inhibited in cotyledons, is also discussed. This article is part of the theme issue 'Retrograde signalling from endosymbiotic organelles'.
doi_str_mv 10.1098/rstb.2019.0399
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7209951</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2398162742</sourcerecordid><originalsourceid>FETCH-LOGICAL-c539t-46859d48219443b0902da2e2cb0e0c7247893a1a2d4115e94525ea941d1f28c93</originalsourceid><addsrcrecordid>eNptkktvEzEUhS1ERUPLliXykgUT_JqHWSBVVSlIVdtFu7Yc-yYxmrEH2wPkf_YH1ZOUCiRWtny_e-7R9UHoLSVLSmT3Maa8WjJC5ZJwKV-gBRUtrZhsyUu0ILJhVSd4c4xep_SdECLrVrxCx5zxhrGmWaCHuy3gsdcpO4tz1D6Z6MbsgseDNlvnIe6w9ha7nLAJIVrn9b78y-UtzqUbfo8RUprfwhr7yfSgI96ADwN8wrcH7erCm2DB4tvQ7waIOsEHfH1g_1Pbj5zFL_cyCd8XZBr7AtFqAOt0LtcIOYZN1BaKtWGYvDN7b6foaK37BG-ezhN0_-Xi7vxrdXVz-e387KoyNZe5Ek1XSys6RqUQfEUkYVYzYGZFgJiWibaTXFPNrKC0BilqVoOWglq6Zp2R_AR9PuiO06qYMuDLBns1RjfouFNBO_Vvxbut2oSfqmVEypoWgfdPAjH8mCBlNbhkoO-1hzAlxbjsaMNawQq6PKAmhpQirJ_HUKLmKKg5CmqOgpqjUBre_W3uGf_z9_wRX1C2lw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2398162742</pqid></control><display><type>article</type><title>The plastid transcription machinery and its coordination with the expression of nuclear genome: Plastid-Encoded Polymerase, Nuclear-Encoded Polymerase and the Genomes Uncoupled 1-mediated retrograde communication</title><source>JSTOR Archival Journals and Primary Sources Collection</source><source>PubMed Central</source><creator>Tadini, Luca ; Jeran, Nicolaj ; Peracchio, Carlotta ; Masiero, Simona ; Colombo, Monica ; Pesaresi, Paolo</creator><creatorcontrib>Tadini, Luca ; Jeran, Nicolaj ; Peracchio, Carlotta ; Masiero, Simona ; Colombo, Monica ; Pesaresi, Paolo</creatorcontrib><description>Plastid genes in higher plants are transcribed by at least two different RNA polymerases, the plastid-encoded RNA polymerase (PEP), a bacteria-like core enzyme whose subunits are encoded by plastid genes ( , , and ), and the nuclear-encoded plastid RNA polymerase (NEP), a monomeric bacteriophage-type RNA polymerase. Both PEP and NEP enzymes are active in non-green plastids and in chloroplasts at all developmental stages. Their transcriptional activity is affected by endogenous and exogenous factors and requires a strict coordination within the plastid and with the nuclear gene expression machinery. This review focuses on the different molecular mechanisms underlying chloroplast transcription regulation and its coordination with the photosynthesis-associated nuclear genes ( ) expression. Particular attention is given to the link between NEP and PEP activity and the GUN1- (Genomes Uncoupled 1) mediated chloroplast-to-nucleus retrograde communication with respect to the adaptive response, i.e. the increased accumulation of NEP-dependent transcripts upon depletion of PEP activity, and the editing-level changes observed in NEP-dependent transcripts, including and , in cotyledons after norflurazon or lincomycin treatment. The role of cytosolic preproteins and HSP90 chaperone as components of the GUN1-retrograde signalling pathway, when chloroplast biogenesis is inhibited in cotyledons, is also discussed. This article is part of the theme issue 'Retrograde signalling from endosymbiotic organelles'.</description><identifier>ISSN: 0962-8436</identifier><identifier>EISSN: 1471-2970</identifier><identifier>DOI: 10.1098/rstb.2019.0399</identifier><identifier>PMID: 32362266</identifier><language>eng</language><publisher>England: The Royal Society</publisher><subject>Cell Nucleus - genetics ; Cell Nucleus - metabolism ; Chloroplasts - genetics ; Chloroplasts - physiology ; DNA-Directed RNA Polymerases - genetics ; DNA-Directed RNA Polymerases - metabolism ; Gene Expression Regulation, Plant - physiology ; Genome, Plant ; Photosynthesis ; Plant Proteins - genetics ; Plant Proteins - metabolism ; Plants - enzymology ; Plants - genetics ; Plastids - genetics ; Plastids - metabolism ; Review ; Signal Transduction - genetics ; Transcription, Genetic - physiology</subject><ispartof>Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2020-06, Vol.375 (1801), p.20190399-20190399</ispartof><rights>2020 The Author(s) 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c539t-46859d48219443b0902da2e2cb0e0c7247893a1a2d4115e94525ea941d1f28c93</citedby><cites>FETCH-LOGICAL-c539t-46859d48219443b0902da2e2cb0e0c7247893a1a2d4115e94525ea941d1f28c93</cites><orcidid>0000-0002-3236-7005</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209951/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209951/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32362266$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tadini, Luca</creatorcontrib><creatorcontrib>Jeran, Nicolaj</creatorcontrib><creatorcontrib>Peracchio, Carlotta</creatorcontrib><creatorcontrib>Masiero, Simona</creatorcontrib><creatorcontrib>Colombo, Monica</creatorcontrib><creatorcontrib>Pesaresi, Paolo</creatorcontrib><title>The plastid transcription machinery and its coordination with the expression of nuclear genome: Plastid-Encoded Polymerase, Nuclear-Encoded Polymerase and the Genomes Uncoupled 1-mediated retrograde communication</title><title>Philosophical transactions of the Royal Society of London. Series B. Biological sciences</title><addtitle>Philos Trans R Soc Lond B Biol Sci</addtitle><description>Plastid genes in higher plants are transcribed by at least two different RNA polymerases, the plastid-encoded RNA polymerase (PEP), a bacteria-like core enzyme whose subunits are encoded by plastid genes ( , , and ), and the nuclear-encoded plastid RNA polymerase (NEP), a monomeric bacteriophage-type RNA polymerase. Both PEP and NEP enzymes are active in non-green plastids and in chloroplasts at all developmental stages. Their transcriptional activity is affected by endogenous and exogenous factors and requires a strict coordination within the plastid and with the nuclear gene expression machinery. This review focuses on the different molecular mechanisms underlying chloroplast transcription regulation and its coordination with the photosynthesis-associated nuclear genes ( ) expression. Particular attention is given to the link between NEP and PEP activity and the GUN1- (Genomes Uncoupled 1) mediated chloroplast-to-nucleus retrograde communication with respect to the adaptive response, i.e. the increased accumulation of NEP-dependent transcripts upon depletion of PEP activity, and the editing-level changes observed in NEP-dependent transcripts, including and , in cotyledons after norflurazon or lincomycin treatment. The role of cytosolic preproteins and HSP90 chaperone as components of the GUN1-retrograde signalling pathway, when chloroplast biogenesis is inhibited in cotyledons, is also discussed. This article is part of the theme issue 'Retrograde signalling from endosymbiotic organelles'.</description><subject>Cell Nucleus - genetics</subject><subject>Cell Nucleus - metabolism</subject><subject>Chloroplasts - genetics</subject><subject>Chloroplasts - physiology</subject><subject>DNA-Directed RNA Polymerases - genetics</subject><subject>DNA-Directed RNA Polymerases - metabolism</subject><subject>Gene Expression Regulation, Plant - physiology</subject><subject>Genome, Plant</subject><subject>Photosynthesis</subject><subject>Plant Proteins - genetics</subject><subject>Plant Proteins - metabolism</subject><subject>Plants - enzymology</subject><subject>Plants - genetics</subject><subject>Plastids - genetics</subject><subject>Plastids - metabolism</subject><subject>Review</subject><subject>Signal Transduction - genetics</subject><subject>Transcription, Genetic - physiology</subject><issn>0962-8436</issn><issn>1471-2970</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNptkktvEzEUhS1ERUPLliXykgUT_JqHWSBVVSlIVdtFu7Yc-yYxmrEH2wPkf_YH1ZOUCiRWtny_e-7R9UHoLSVLSmT3Maa8WjJC5ZJwKV-gBRUtrZhsyUu0ILJhVSd4c4xep_SdECLrVrxCx5zxhrGmWaCHuy3gsdcpO4tz1D6Z6MbsgseDNlvnIe6w9ha7nLAJIVrn9b78y-UtzqUbfo8RUprfwhr7yfSgI96ADwN8wrcH7erCm2DB4tvQ7waIOsEHfH1g_1Pbj5zFL_cyCd8XZBr7AtFqAOt0LtcIOYZN1BaKtWGYvDN7b6foaK37BG-ezhN0_-Xi7vxrdXVz-e387KoyNZe5Ek1XSys6RqUQfEUkYVYzYGZFgJiWibaTXFPNrKC0BilqVoOWglq6Zp2R_AR9PuiO06qYMuDLBns1RjfouFNBO_Vvxbut2oSfqmVEypoWgfdPAjH8mCBlNbhkoO-1hzAlxbjsaMNawQq6PKAmhpQirJ_HUKLmKKg5CmqOgpqjUBre_W3uGf_z9_wRX1C2lw</recordid><startdate>20200622</startdate><enddate>20200622</enddate><creator>Tadini, Luca</creator><creator>Jeran, Nicolaj</creator><creator>Peracchio, Carlotta</creator><creator>Masiero, Simona</creator><creator>Colombo, Monica</creator><creator>Pesaresi, Paolo</creator><general>The Royal Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-3236-7005</orcidid></search><sort><creationdate>20200622</creationdate><title>The plastid transcription machinery and its coordination with the expression of nuclear genome: Plastid-Encoded Polymerase, Nuclear-Encoded Polymerase and the Genomes Uncoupled 1-mediated retrograde communication</title><author>Tadini, Luca ; Jeran, Nicolaj ; Peracchio, Carlotta ; Masiero, Simona ; Colombo, Monica ; Pesaresi, Paolo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c539t-46859d48219443b0902da2e2cb0e0c7247893a1a2d4115e94525ea941d1f28c93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Cell Nucleus - genetics</topic><topic>Cell Nucleus - metabolism</topic><topic>Chloroplasts - genetics</topic><topic>Chloroplasts - physiology</topic><topic>DNA-Directed RNA Polymerases - genetics</topic><topic>DNA-Directed RNA Polymerases - metabolism</topic><topic>Gene Expression Regulation, Plant - physiology</topic><topic>Genome, Plant</topic><topic>Photosynthesis</topic><topic>Plant Proteins - genetics</topic><topic>Plant Proteins - metabolism</topic><topic>Plants - enzymology</topic><topic>Plants - genetics</topic><topic>Plastids - genetics</topic><topic>Plastids - metabolism</topic><topic>Review</topic><topic>Signal Transduction - genetics</topic><topic>Transcription, Genetic - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tadini, Luca</creatorcontrib><creatorcontrib>Jeran, Nicolaj</creatorcontrib><creatorcontrib>Peracchio, Carlotta</creatorcontrib><creatorcontrib>Masiero, Simona</creatorcontrib><creatorcontrib>Colombo, Monica</creatorcontrib><creatorcontrib>Pesaresi, Paolo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Philosophical transactions of the Royal Society of London. Series B. Biological sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tadini, Luca</au><au>Jeran, Nicolaj</au><au>Peracchio, Carlotta</au><au>Masiero, Simona</au><au>Colombo, Monica</au><au>Pesaresi, Paolo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The plastid transcription machinery and its coordination with the expression of nuclear genome: Plastid-Encoded Polymerase, Nuclear-Encoded Polymerase and the Genomes Uncoupled 1-mediated retrograde communication</atitle><jtitle>Philosophical transactions of the Royal Society of London. Series B. Biological sciences</jtitle><addtitle>Philos Trans R Soc Lond B Biol Sci</addtitle><date>2020-06-22</date><risdate>2020</risdate><volume>375</volume><issue>1801</issue><spage>20190399</spage><epage>20190399</epage><pages>20190399-20190399</pages><issn>0962-8436</issn><eissn>1471-2970</eissn><abstract>Plastid genes in higher plants are transcribed by at least two different RNA polymerases, the plastid-encoded RNA polymerase (PEP), a bacteria-like core enzyme whose subunits are encoded by plastid genes ( , , and ), and the nuclear-encoded plastid RNA polymerase (NEP), a monomeric bacteriophage-type RNA polymerase. Both PEP and NEP enzymes are active in non-green plastids and in chloroplasts at all developmental stages. Their transcriptional activity is affected by endogenous and exogenous factors and requires a strict coordination within the plastid and with the nuclear gene expression machinery. This review focuses on the different molecular mechanisms underlying chloroplast transcription regulation and its coordination with the photosynthesis-associated nuclear genes ( ) expression. Particular attention is given to the link between NEP and PEP activity and the GUN1- (Genomes Uncoupled 1) mediated chloroplast-to-nucleus retrograde communication with respect to the adaptive response, i.e. the increased accumulation of NEP-dependent transcripts upon depletion of PEP activity, and the editing-level changes observed in NEP-dependent transcripts, including and , in cotyledons after norflurazon or lincomycin treatment. The role of cytosolic preproteins and HSP90 chaperone as components of the GUN1-retrograde signalling pathway, when chloroplast biogenesis is inhibited in cotyledons, is also discussed. This article is part of the theme issue 'Retrograde signalling from endosymbiotic organelles'.</abstract><cop>England</cop><pub>The Royal Society</pub><pmid>32362266</pmid><doi>10.1098/rstb.2019.0399</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0002-3236-7005</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0962-8436
ispartof Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2020-06, Vol.375 (1801), p.20190399-20190399
issn 0962-8436
1471-2970
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7209951
source JSTOR Archival Journals and Primary Sources Collection; PubMed Central
subjects Cell Nucleus - genetics
Cell Nucleus - metabolism
Chloroplasts - genetics
Chloroplasts - physiology
DNA-Directed RNA Polymerases - genetics
DNA-Directed RNA Polymerases - metabolism
Gene Expression Regulation, Plant - physiology
Genome, Plant
Photosynthesis
Plant Proteins - genetics
Plant Proteins - metabolism
Plants - enzymology
Plants - genetics
Plastids - genetics
Plastids - metabolism
Review
Signal Transduction - genetics
Transcription, Genetic - physiology
title The plastid transcription machinery and its coordination with the expression of nuclear genome: Plastid-Encoded Polymerase, Nuclear-Encoded Polymerase and the Genomes Uncoupled 1-mediated retrograde communication
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T14%3A55%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20plastid%20transcription%20machinery%20and%20its%20coordination%20with%20the%20expression%20of%20nuclear%20genome:%20Plastid-Encoded%20Polymerase,%20Nuclear-Encoded%20Polymerase%20and%20the%20Genomes%20Uncoupled%201-mediated%20retrograde%20communication&rft.jtitle=Philosophical%20transactions%20of%20the%20Royal%20Society%20of%20London.%20Series%20B.%20Biological%20sciences&rft.au=Tadini,%20Luca&rft.date=2020-06-22&rft.volume=375&rft.issue=1801&rft.spage=20190399&rft.epage=20190399&rft.pages=20190399-20190399&rft.issn=0962-8436&rft.eissn=1471-2970&rft_id=info:doi/10.1098/rstb.2019.0399&rft_dat=%3Cproquest_pubme%3E2398162742%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c539t-46859d48219443b0902da2e2cb0e0c7247893a1a2d4115e94525ea941d1f28c93%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2398162742&rft_id=info:pmid/32362266&rfr_iscdi=true