Dialysis‐associated allergic reactions during continuous renal replacement therapy and hemodialysis: A case report

Dialyzer reactions are long‐appreciated complications of dialysis. Despite advances in dialysis machines and membranes, these life‐threatening reactions still occur. It is imperative to recognize potential dialyzer reactions when assessing adverse dialysis events as reexposure to dialytic treatments...

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Bibliographic Details
Published in:Hemodialysis international 2020-01, Vol.24 (1), p.E5-E9
Main Authors: Chen, Dhruti P., Flythe, Jennifer E.
Format: Article
Language:English
Subjects:
Aged
allergic reaction
Anaphylaxis - chemically induced
Continuous Renal Replacement Therapy - adverse effects
dialyzer reaction
Female
hemodialysis
Humans
hypotension
Renal Dialysis - adverse effects
safety issues
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Summary:Dialyzer reactions are long‐appreciated complications of dialysis. Despite advances in dialysis machines and membranes, these life‐threatening reactions still occur. It is imperative to recognize potential dialyzer reactions when assessing adverse dialysis events as reexposure to dialytic treatments could be life threatening. We present the case of a 72‐year old woman with dialysis‐requiring anuric acute kidney injury who experienced acute hypotension and cardiopulmonary arrest during both continuous renal replacement therapy and a subsequent hemodialysis treatment. We concluded that she had an anaphylactic reaction to an unidentified component of the dialysis equipment. Identification, work up, treatment, and reporting of dialyzer reactions are discussed in the context of this case.
ISSN:1492-7535
1542-4758
DOI:10.1111/hdi.12801