Leukoerythroblastic reaction in a patient with COVID‐19 infection

The peripheral blood smear was consistent with a leukoerythroblastic picture with normocytic anemia with occasional nucleated red blood cells (Image 1A), mild anisocytosis, and rare dacrocytes. Leukoerythroblastosis can rarely be seen in viral infections such as parvovirus.1, 2 Corona virus disease...

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Bibliographic Details
Published in:American Journal of Hematology 2020-08, Vol.95 (8), p.999-1000
Main Authors: Mitra, Anupam, Dwyre, Denis M., Schivo, Michael, Thompson, George R., Cohen, Stuart H., Ku, Nam, Graff, John P.
Format: Article
Language:English
Subjects:
Anemia, Myelophthisic - blood
Betacoronavirus
Clinical Pearls in Blood Diseases
Coronavirus Infections - blood
COVID-19
Erythroblasts - pathology
Female
Granulocyte Precursor Cells - pathology
Hematology
Humans
Images in Hematology
Middle Aged
Pandemics
Pneumonia, Viral - blood
SARS-CoV-2
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Summary:The peripheral blood smear was consistent with a leukoerythroblastic picture with normocytic anemia with occasional nucleated red blood cells (Image 1A), mild anisocytosis, and rare dacrocytes. Leukoerythroblastosis can rarely be seen in viral infections such as parvovirus.1, 2 Corona virus disease 2019 (COVID‐19) is an infectious viral disease caused by a pathogen named severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).3 Note, COVID‐19 has created a public health emergency in many countries, including the United States, and is expected to continue to spread. Few strains of corona virus are known to cause flu‐like upper respiratory illnesses in humans, but the current strain, SARS‐CoV‐2, was not known to cause any human illnesses prior to this outbreak. [...]very little information about COVID‐19's pathogenic role in humans is known.
ISSN:0361-8609
1096-8652
DOI:10.1002/ajh.25793