Dural Marginal Zone Lymphoma in a Patient With a Hepatitis C Virus Infection

Primary dural marginal zone lymphomas (MZLs) are exceptionally rare, with fewer than 100 cases reported to date. While the association between hepatitis C virus (HCV) infection and lymphoma is well established, it is unclear if this association extends to all anatomic sites. Here we report a case of...

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Bibliographic Details
Published in:World journal of oncology 2020-06, Vol.11 (3), p.122-125
Main Authors: Villaume, Matthew T., Patel, Dilan, Lopez, Christine, Patel, Vivek, Diggs, Pauleatha, Harmsen, Hannah, Thompson, Mary Ann, Morgan, David
Format: Article
Language:English
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Case Report
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Summary:Primary dural marginal zone lymphomas (MZLs) are exceptionally rare, with fewer than 100 cases reported to date. While the association between hepatitis C virus (HCV) infection and lymphoma is well established, it is unclear if this association extends to all anatomic sites. Here we report a case of dural MZL in a 61-year-old woman with an HCV infection. To our knowledge, this is the first report of a dural MZL associated with an HCV infection in an immunocompetent patient and was successfully treated with radiotherapy and rituximab. As such, future cases of primary MZL found in the dura should prompt consideration of co-infection with microbials such as HCV and upfront treatment with anti-virals should be considered.
ISSN:1920-4531
1920-454X
DOI:10.14740/wjon1285