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Dural Marginal Zone Lymphoma in a Patient With a Hepatitis C Virus Infection

Primary dural marginal zone lymphomas (MZLs) are exceptionally rare, with fewer than 100 cases reported to date. While the association between hepatitis C virus (HCV) infection and lymphoma is well established, it is unclear if this association extends to all anatomic sites. Here we report a case of...

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Published in:World journal of oncology 2020-06, Vol.11 (3), p.122-125
Main Authors: Villaume, Matthew T., Patel, Dilan, Lopez, Christine, Patel, Vivek, Diggs, Pauleatha, Harmsen, Hannah, Thompson, Mary Ann, Morgan, David
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container_issue 3
container_start_page 122
container_title World journal of oncology
container_volume 11
creator Villaume, Matthew T.
Patel, Dilan
Lopez, Christine
Patel, Vivek
Diggs, Pauleatha
Harmsen, Hannah
Thompson, Mary Ann
Morgan, David
description Primary dural marginal zone lymphomas (MZLs) are exceptionally rare, with fewer than 100 cases reported to date. While the association between hepatitis C virus (HCV) infection and lymphoma is well established, it is unclear if this association extends to all anatomic sites. Here we report a case of dural MZL in a 61-year-old woman with an HCV infection. To our knowledge, this is the first report of a dural MZL associated with an HCV infection in an immunocompetent patient and was successfully treated with radiotherapy and rituximab. As such, future cases of primary MZL found in the dura should prompt consideration of co-infection with microbials such as HCV and upfront treatment with anti-virals should be considered.
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title Dural Marginal Zone Lymphoma in a Patient With a Hepatitis C Virus Infection
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