Refractory adult Coats disease treated with dexamethasone intravitreal implant: A case report

Coats disease is a sporadic, retinal vascular abnormality, causing blindness. Several interventional methods, including laser photocoagulation, have been proposed; however, the use of intravitreal dexamethasone in refractory Coats disease is not well described. A 38-year-old man presented with a pai...

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Bibliographic Details
Published in:Medicine (Baltimore) 2020-05, Vol.99 (20), p.e20249-e20249
Main Authors: Ding, Yu-Hua, Yao, Bang-Tao, Zhao, Xiao-Gui, Yu, Hao, Liu, Gang, Wang, Xiu-Ying
Format: Article
Language:English
Subjects:
Adult
Clinical Case Report
Dexamethasone - therapeutic use
Female
Glucocorticoids - therapeutic use
Humans
Intravitreal Injections - methods
Male
Middle Aged
Recurrence
Retinal Telangiectasis - drug therapy
Retinal Telangiectasis - physiopathology
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Summary:Coats disease is a sporadic, retinal vascular abnormality, causing blindness. Several interventional methods, including laser photocoagulation, have been proposed; however, the use of intravitreal dexamethasone in refractory Coats disease is not well described. A 38-year-old man presented with a painless reduction in visual acuity in his right eye, commencing 15 days prior to initial assessment. Clinical manifestations and multimodal imaging indicated Coats disease. Retinal laser photocoagulation was performed in the nonperfused areas, 15 months later, the exudative retinal detachment, and macular edema remained, the patient was then treated with an intravitreal slow-release dexamethasone implant. The exudative retinal detachment and macular edema had resolved, and the BCVA had also improved. Dexamethasone intravitreal implantation was effective in treating refractory Coats disease.
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000020249