Correlation between thromboelastography and rotational thromboelastometry values in adult liver transplant recipients

• Published in: Indian journal of anaesthesia 2020-04, Vol.64 (4), p.286-291, Article 286
• Main Authors: Singh, Shweta, Krishnan, Gopi, Ashraf, Hashir, Subramanian, Rajkumar, Pandey, Vijaykant, Nasa, Vaibhav, Goyal, Sumit, Gupta, Subhash
• Format: Article
• Language: English
• Subjects: Case management; Diseases; Laboratories; Liver diseases; Liver transplantation; Liver transplants; Organ transplant recipients; Organ transplantation; Original; Surgery; Tissue donation
• ISSN: 0019-5049; 0976-2817
• DOI: 10.4103/ija.IJA_762_19

Background and Aims: Viscoelastic haemostatic assays (VHA) namely Thromboelastogram (TEG) and Rotational thromboelastometry (ROTEM) are used for global assessment of coagulopathy and guiding transfusion during living donor liver transplant (LDLT).We conducted a study to compare the interchangeability of the values obtained from these devices in patients with End stage liver disease (ESLD) undergoing LDLT. Methods: In 76 patients undergoing LDLT, ROTEM and TEG were performed and assessed for interchangeability using Spearman Correlation. The direction and strength of correlation between equivalent parameters was calculated using Inter Class Correlation (ICC) and Bland Altman analysis. Results: The correlation ρ between CT (clotting time) of ROTEM and R of TEG was 0.16 (P = 0.19).The ICC was 0.15, with 95% confidence interval (CI) of -0.38-0.48 (P = 0.25).The ρ of CFT (ROTEM) with K (TEG) was 0.425 (P=