Conjunctivitis and COVID‐19: A meta‐analysis

There are sparse data in literature regarding conjunctivitis incidence in COVID‐19 and its relationship with disease severity. The objective of this metanalysis was to assess the association between conjunctivitis and the severity of COVID‐19 disease. Methods We performed a meta‐analysis with studie...

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Bibliographic Details
Published in:Journal of Medical Virology 2020-09, Vol.92 (9), p.1413-1414
Main Authors: Loffredo, Lorenzo, Pacella, Fernanda, Pacella, Elena, Tiscione, Giulia, Oliva, Alessandra, Violi, Francesco
Format: Article
Language:English
Subjects:
Aged
China
Conjunctivitis
Conjunctivitis - virology
COVID-19
COVID-19 - complications
Female
Humans
Letter to the Editor
Letters to the Editor
Male
Middle Aged
Virology
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Summary:There are sparse data in literature regarding conjunctivitis incidence in COVID‐19 and its relationship with disease severity. The objective of this metanalysis was to assess the association between conjunctivitis and the severity of COVID‐19 disease. Methods We performed a meta‐analysis with studies that included patients with severe vs non‐severe form of COVID‐19 infection. Severe COVID‐19 infection was defined as severe pneumonia, mortality, acute respiratory distress syndrome (ARDS), use of mechanical ventilation or Intensive Care Unit (ICU) treatment. Results Three studies, including 1167 patients, reported the incidence of conjunctivitis at admission to the hospital. The overall rate of conjunctivitis was 1.1%; it was 3% and 0.7% in severe and non‐severe COVID‐19 patients, respectively. Patients with severe COVID‐19 had an increased incidence of conjunctivitis (O.R.:3.4; 95% C.I.:1.1‐10.2; p=0.030). Conclusions Conjunctivitis is more frequent in severe COVID and may be a warning sign of poor outcomes.
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.25938