Phylotranscriptomics of the Pentapetalae Reveals Frequent Regulatory Variation in Plant Local Responses to the Fungal Pathogen Sclerotinia sclerotiorum

• Published in: The Plant cell 2020-06, Vol.32 (6), p.1820-1844
• Main Authors: Sucher, Justine, Mbengue, Malick, Dresen, Axel, Barascud, Marielle, Didelon, Marie, Barbacci, Adelin, Raffaele, Sylvain
• Format: Article
• Language: English
• Subjects: Arabidopsis - microbiology; Ascomycota - pathogenicity; Disease Resistance - genetics; Disease Resistance - physiology; Evolution, Molecular; Gene Expression Regulation, Plant; Large-Scale Biology; Life Sciences; Plant Diseases - microbiology; Plant Immunity - physiology
• ISSN: 1040-4651; 1532-298X
• DOI: 10.1105/tpc.19.00806

Quantitative disease resistance (QDR) is a conserved form of plant immunity that limits infections caused by a broad range of pathogens. QDR has a complex genetic determinism. The extent to which molecular components of the QDR response vary across plant species remains elusive. The fungal pathogen , causal agent of white mold diseases on hundreds of plant species, triggers QDR in host populations. To document the diversity of local responses to at the molecular level, we analyzed the complete transcriptomes of six species spanning the Pentapetalae ( , , Arabidopsis [ ], , , and ) inoculated with the same strain of About one-third of plant transcriptomes responded locally to , including a high proportion of broadly conserved genes showing frequent regulatory divergence at the interspecific level. Evolutionary inferences suggested a trend toward the acquisition of gene induction relatively recently in several lineages. Focusing on a group of ABCG transporters, we propose that exaptation by regulatory divergence contributed to the evolution of QDR. This evolutionary scenario has implications for understanding the QDR spectrum and durability. Our work provides resources for functional studies of gene regulation and QDR molecular mechanisms across the Pentapetalae.