Interleukin-6 and Melatonin as Predictors of Cognitive, Emotional and Functional Ageing of Older People

The ageing process causes a number of changes in the human immune and endocrine systems. The aim of this study was to assess the relationship between cognitive, emotional and functional skills as well lifestyle, versus selected biochemical indicators of the ageing process. The cross-sectional study...

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Published in:International journal of environmental research and public health 2020-05, Vol.17 (10), p.3623
Main Authors: Kurowska, Anna, Bodys-Cupak, Iwona, Staszkiewicz, Magdalena, Szklarczyk, Joanna, Zalewska-Puchała, Joanna, Kliś-Kalinowska, Anna, Makara-Studzińska, Marta, Majda, Anna
Format: Article
Language:English
Subjects:
Activities of Daily Living
Age
Aged
Aged, 80 and over
Aging
Antioxidants
Biomarkers - blood
Blood plasma
Cognition
Cognition & reasoning
Cognitive ability
Consent
Cross-Sectional Studies
Cytokines
Disease
Emotions
Endocrine system
Female
Forecasting
Geriatrics
Health care
Health services
Humans
Interleukin 6
Interleukin-6 - blood
Lifestyles
Male
Melatonin
Melatonin - blood
Mental disorders
Middle Aged
Older people
Oxidative stress
Poland
R&D
Research & development
Skills
Studies
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cited_by cdi_FETCH-LOGICAL-c418t-1ce2018b9a159442c4e3f9bf1e9fec0e55bb2f98a0142b476d723f8d2f5265483
cites cdi_FETCH-LOGICAL-c418t-1ce2018b9a159442c4e3f9bf1e9fec0e55bb2f98a0142b476d723f8d2f5265483
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container_issue 10
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container_title International journal of environmental research and public health
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creator Kurowska, Anna
Bodys-Cupak, Iwona
Staszkiewicz, Magdalena
Szklarczyk, Joanna
Zalewska-Puchała, Joanna
Kliś-Kalinowska, Anna
Makara-Studzińska, Marta
Majda, Anna
description The ageing process causes a number of changes in the human immune and endocrine systems. The aim of this study was to assess the relationship between cognitive, emotional and functional skills as well lifestyle, versus selected biochemical indicators of the ageing process. The cross-sectional study was conducted in a group of 121 people aged 60-90 residing in the Lesser Poland voivodship. The study used standardized research tools including the Barthel scale, Instrumental Activities of Daily Living (IADL) scale, Mini-Mental State Examination (MMSE), Life Orientation Test (LOT-R) and inventory of health behaviors (IHB). In addition, the concentration of IL-6 and melatonin in the blood plasma was determined. We determined the correlation between the level of IL-6 in a group of people over 75 years of age (requiring medical care), and results of the IADL scale. There was also a correlation between melatonin levels and the MMSE results in a group of people aged 60-75 who did not require constant medical care. IL-6 can be treated as a predictor of functional skills of people over 75 years of age, and melatonin can be perceived as a factor for recognizing cognitive impairment in elderly people who do not require constant medical assistance.
doi_str_mv 10.3390/ijerph17103623
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subjects Activities of Daily Living
Age
Aged
Aged, 80 and over
Aging
Antioxidants
Biomarkers - blood
Blood plasma
Cognition
Cognition & reasoning
Cognitive ability
Consent
Cross-Sectional Studies
Cytokines
Disease
Emotions
Endocrine system
Female
Forecasting
Geriatrics
Health care
Health services
Humans
Interleukin 6
Interleukin-6 - blood
Lifestyles
Male
Melatonin
Melatonin - blood
Mental disorders
Middle Aged
Older people
Oxidative stress
Poland
R&D
Research & development
Skills
Studies
title Interleukin-6 and Melatonin as Predictors of Cognitive, Emotional and Functional Ageing of Older People
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