Association of “initial CT” findings with mortality in older patients with coronavirus disease 2019 (COVID-19)

• Published in: European radiology 2020-11, Vol.30 (11), p.6186-6193
• Main Authors: Li, Yan, Yang, Zhenlu, Ai, Tao, Wu, Shandong, Xia, Liming
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Betacoronavirus; Chest; China - epidemiology; Coronavirus Infections - diagnostic imaging; Coronavirus Infections - mortality; COVID-19; Diagnostic Radiology; Female; Geriatric Assessment - methods; Geriatric Assessment - statistics & numerical data; Humans; Imaging; Internal Medicine; Interventional Radiology; Lung - diagnostic imaging; Male; Medicine; Medicine & Public Health; Middle Aged; Neuroradiology; Pandemics; Pneumonia, Viral - diagnostic imaging; Pneumonia, Viral - mortality; Prognosis; Radiology; Reproducibility of Results; Retrospective Studies; ROC Curve; SARS-CoV-2; Sensitivity and Specificity; Tomography, X-Ray Computed - methods; Ultrasound
• ISSN: 0938-7994; 1432-1084
• DOI: 10.1007/s00330-020-06969-5

Objectives To investigate the association of chest CT findings with mortality in clinical management of older patients. Methods From January 21 to February 14, 2020, 98 older patients (≥ 60 years) who had undergone chest CT scans (“initial CT”) on admission were enrolled. Manifestation and CT score were compared between the death group and the survival group. In each group, patients were sub-grouped based on the time interval between symptom onset and the “initial CT” scan: subgroup1 (interval ≤ 5 days), subgroup2 (interval between 6 and 10 days), and subgroup3 (interval > 10 days). Adjusted ROC curve after adjustment for age and gender was applied. Results Consolidations on CT images were more common in the death group ( n  = 46) than in the survival group ( n  = 52) (53.2% vs 32.0%, p