Association between Periodontitis and High Blood Pressure: Results from the Study of Periodontal Health in Almada-Seixal (SoPHiAS)

Periodontitis is a common chronic inflammatory disease which could have an important impact on blood pressure (BP). This study aimed to explore (a) the association between periodontal health and BP in a large representative cohort, (b) the predictive value of diagnosis of periodontitis in undiagnose...

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Bibliographic Details
Published in:Journal of clinical medicine 2020-05, Vol.9 (5), p.1585
Main Authors: Machado, Vanessa, Aguilera, Eva Muñoz, Botelho, João, Hussain, Syed Basit, Leira, Yago, Proença, Luís, D'Aiuto, Francesco, Mendes, José João
Format: Article
Language:English
Subjects:
Age
Antihypertensives
Blood pressure
Body mass index
Clinical medicine
Gender
Gum disease
Hypertension
Metropolitan areas
Patients
Questionnaires
Regression analysis
Sociodemographics
Teeth
Variables
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Summary:Periodontitis is a common chronic inflammatory disease which could have an important impact on blood pressure (BP). This study aimed to explore (a) the association between periodontal health and BP in a large representative cohort, (b) the predictive value of diagnosis of periodontitis in undiagnosed raised BP and (c) whether age is a mediator of this relationship. In total, 1057 randomly recruited individuals (mean age, 60.9 ± 16.3 years, 57.7% women) underwent periodontal clinical assessment and one-single BP measurement using an automated sphygmomanometer device. Logistic and linear regression models were used to estimate the odds of hypertension based on periodontitis case definitions. Mediation analysis was performed to understand the effect of age on the association of periodontitis with hypertension. Adjusted logistic model for gender, smoking habits and body mass index confirmed the association between high BP and periodontitis (OR = 2.31, 95%CI: 1.75-3.04, < 0.001). Among 168 participants with undiagnosed high BP (15.9% of the study sample), 62.5% had periodontitis ( = 105). In this study, the association between periodontitis with both systolic blood pressure (SBP) (77.6%, < 0.001) and diastolic blood pressure (DBP) (66.0%, < 0.001) was mediated by age. Periodontitis is closely linked to BP in a representative Portuguese population.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm9051585