Physiological Traits and Adherence to Obstructive Sleep Apnea Treatment in Patients with Stroke

The physiological traits and adherence to patients with obstructive sleep apnea (OSA), is examined. The treatment in OSA patients with stroke may improve neurological recovery. However, trials of OSA treatment are limited by decreased adherence to continuous positive airway pressure (CPAP). Psychoso...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2020-06, Vol.201 (12), p.1568-1572
Main Authors: Zinchuk, Andrey V, Redeker, Nancy S, Chu, Jen-Hwa, Liang, Jiasheng, Stepnowsky, Carl, Brandt, Cynthia A, Bravata, Dawn M, Wellman, Andrew, Sands, Scott A, Yaggi, Henry K
Format: Article
Language:English
Subjects:
Aged
Airway management
Arousal - physiology
Continuous Positive Airway Pressure
Correspondence
Feedback, Physiological
Female
Humans
Male
Medical treatment
Middle Aged
Patient Compliance
Pharynx - physiopathology
Polysomnography
Randomized Controlled Trials as Topic
Sleep apnea
Sleep Apnea, Obstructive - complications
Sleep Apnea, Obstructive - physiopathology
Sleep Apnea, Obstructive - therapy
Stroke
Stroke - complications
Stroke - physiopathology
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Summary:The physiological traits and adherence to patients with obstructive sleep apnea (OSA), is examined. The treatment in OSA patients with stroke may improve neurological recovery. However, trials of OSA treatment are limited by decreased adherence to continuous positive airway pressure (CPAP). Psychosocial factors in nonstroke patients includes sleepiness and comorbidities predict adherence. Information about recent reports also indicate that low arousal threshold, a physiologic trait of OSA, is linked with reduced rates in the use of regular CPAP. A hypothesis showed that physiologic OSA traits are related with CPAP adherence and improve models of adherence based on established factors such as demographic, social, comorbidities and polysomnographic metrics. An overview on the methods of performance for a secondary data analysis of a randomized controlled trial among patients with acute stroke or transient ischemic attack (TIA), is also provided.
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.201911-2203LE