Oxidative contribution of air pollution to extrinsic skin ageing

[Display omitted] •Epidemiological evidence links exposure to poor air quality to lentigines and wrinkles.•Experimental studies provide mechanistic explanations involving oxidative stress.•Polluted air may hasten skin ageing through indirect systemic effects via the lung and/or direct effects on cut...

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Bibliographic Details
Published in:Free radical biology & medicine 2020-05, Vol.151, p.111-122
Main Authors: Fussell, Julia C., Kelly, Frank J.
Format: Article
Language:English
Subjects:
Ageing
Air Pollutants - toxicity
Air pollution
Air Pollution - adverse effects
Air Pollution - analysis
Nitrogen dioxide
Nitrogen Dioxide - analysis
Oxidative Stress
Ozone
Particulate Matter - analysis
Particulate Matter - toxicity
Skin
Skin Aging
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Summary:[Display omitted] •Epidemiological evidence links exposure to poor air quality to lentigines and wrinkles.•Experimental studies provide mechanistic explanations involving oxidative stress.•Polluted air may hasten skin ageing through indirect systemic effects via the lung and/or direct effects on cutaneous tissue.•Prevention measures would need to combine strategies that target both ‘routes’.•Air pollution is one of several environmental stressors that combined, may have additive/synergistic effects on the skin.
ISSN:0891-5849
1873-4596
1873-4596
DOI:10.1016/j.freeradbiomed.2019.11.038