Buccal region’s Kimura disease in a pediatric patient: A case report and review of the literatture

• Published in: International journal of surgery case reports 2020-01, Vol.72, p.584-586
• Main Authors: Ahmed Brahim, Ahmedou, Iziki, Omar, Abada, Reda, Mohamed, Roubal, Mohamed, Mahtar
• Format: Article
• Language: English
• Subjects: Kimura disease; Oral cavity; Pediatric patient; Surgical resection; Systemic steroid therapy
• ISSN: 2210-2612; 2210-2612
• DOI: 10.1016/j.ijscr.2020.05.075

•Kimura disease is a chronic inflammatory disease.•The occurrence of kimura disease in the oral cavity is extremely rare.•The Etiology Of The Kimura Disease Is Unknown.•The diagnosis of kimura disease is confirmed by surgical biopsy.•Treatment of kimura disease is variable. Kimura disease is a chronic inflammatory disorder that mainly manifests as a swelling in the neck region AlGhamdi et al. (2016). However, its occurrence in the oral cavity is extremely rare Lee et al. (2017). It usually affects young men of Asian race but it is rare in other races Fouda et al. (2010). We report an extremely rare case of Kimura disease of the buccal region in a pediatric patient. The treatment consists of surgery combined with systemic steroid therapy. The etiology of KD is unknown. Although the presence of eosinophilia and increased IgE, tumor necrosis factor (TNF)-a, interleukin (IL)-4, IL-5, IL-13 levels, and mast cells in peripheral blood, as well as in the affected tissue, were observed in patients Sun et al. (2008). No specific antigens have been identified. The optimal management strategy for KD has not yet been established. The treatment is variable Fouda et al. (2010) and Su et al. (2019). It includes surgical excision, regional, or systemic steroid therapy, and radiotherapy Sun et al. (2008). KD is a rare chronic inflammatory disorder of unknown etiology Fouda et al. (2010) and Kim and Szeto (1937). The diagnosis can be only confirmed by histopathological features.