The clinical course of SARS-CoV-2 positive neonates

The COVID-19 pneumonia was firstly reported in Wuhan, China, in December 2019. The disease had a rapid spread all over the word becoming an international public health emergency. Limited data were available on COVID-19 positive neonates. We reviewed relevant literature to understand the clinical cou...

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Bibliographic Details
Published in:Journal of perinatology 2020-10, Vol.40 (10), p.1462-1469
Main Authors: De Bernardo, Giuseppe, Giordano, Maurizio, Zollo, Giada, Chiatto, Fabrizia, Sordino, Desiree, De Santis, Rita, Perrone, Serafina
Format: Article
Language:English
Subjects:
692/1807/1809
692/699/255/2514
Betacoronavirus - isolation & purification
Coronavirus Infections - diagnosis
Coronavirus Infections - physiopathology
Coronavirus Infections - transmission
Coronaviruses
Cough
COVID-19
Disease transmission
Fever
Health aspects
Humans
Infant, Newborn
Infant, Newborn, Diseases - diagnosis
Infant, Newborn, Diseases - physiopathology
Infants (Newborn)
Infection Control
Infectious Disease Transmission, Vertical - prevention & control
Medicine
Medicine & Public Health
Neonates
Neonatology
Newborn babies
Pandemics
Pediatric Surgery
Pediatrics
Pneumonia, Viral - diagnosis
Pneumonia, Viral - physiopathology
Pneumonia, Viral - transmission
Prognosis
Public health
Review
Review Article
SARS-CoV-2
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Signs and symptoms
Viral diseases
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Description
Summary:The COVID-19 pneumonia was firstly reported in Wuhan, China, in December 2019. The disease had a rapid spread all over the word becoming an international public health emergency. Limited data were available on COVID-19 positive neonates. We reviewed relevant literature to understand the clinical course of disease and transmission routes in affected neonates. The aim of the study was evaluating the clinical course and prognosis of SARS-CoV-2 positive neonates. Based on current literature, the hypothesis of vertical transmission of SARS-CoV-2, though conceivable, remains unproven. A research conducted on PubMed database from December 2019 to April 27, 2020 revealed that were reported 25 neonates affected by SARS-CoV-2. Main symptoms were fever, cough, or shortness of breath but often these neonates did not show other symptoms during length stay in hospital. No deaths occurred.
ISSN:0743-8346
1476-5543
1476-5543
DOI:10.1038/s41372-020-0715-0