Language lateralization from task‐based and resting state functional MRI in patients with epilepsy

We compared resting state (RS) functional connectivity and task‐based fMRI to lateralize language dominance in 30 epilepsy patients (mean age = 33; SD = 11; 12 female), a measure used for presurgical planning. Language laterality index (LI) was calculated from task fMRI in frontal, temporal, and fro...

Full description

Saved in:
Bibliographic Details
Published in:Human brain mapping 2020-08, Vol.41 (11), p.3133-3146
Main Authors: Rolinski, Rachel, You, Xiaozhen, Gonzalez‐Castillo, Javier, Norato, Gina, Reynolds, Richard C., Inati, Sara K., Theodore, William H.
Format: Article
Language:English
Subjects:
Brain mapping
Broca's area
Cerebral dominance
Cerebral hemispheres
Dominance
Epilepsy
fMRI
Frontal lobe
functional laterality
Functional magnetic resonance imaging
Hemispheric laterality
Language
magnetic resonance imaging
Masks
Mathematical analysis
Neural networks
resting state
Seizures
Statistical methods
Thresholds
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We compared resting state (RS) functional connectivity and task‐based fMRI to lateralize language dominance in 30 epilepsy patients (mean age = 33; SD = 11; 12 female), a measure used for presurgical planning. Language laterality index (LI) was calculated from task fMRI in frontal, temporal, and frontal + temporal regional masks using LI bootstrap method from SPM12. RS language LI was assessed using two novel methods of calculating RS language LI from bilateral Broca's area seed based connectivity maps across regional masks and multiple thresholds (p 
ISSN:1065-9471
1097-0193
DOI:10.1002/hbm.25003